Felodipine Tablets
Function and Efficacy
This product is a selective calcium ion antagonist, which mainly inhibits the influx of extracellular calcium in arteriolar smooth muscle cells, selectively dilates arterioles, has no such effect on veins, does not cause postural hypotension, and has no significant inhibitory effect on the myocardium. While reducing renal vascular resistance, this product does not affect the glomerular filtration rate and creatinine clearance rate, and the renal blood flow remains unchanged or even slightly increases, and has a natriuretic and diuretic effect. This product can increase output and cardiac index, significantly reduce afterload, and has no significant effect on cardiac contractile function, preload and heart rate.
Ingredients
The main ingredient of this product is felodipine, and its chemical name is 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinedicarboxylic acid ethyl ester methyl ester.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| FelodipineIngredients |
Selective calcium ion antagonists mainly inhibit the influx of extracellular calcium into arteriolar smooth muscle cells, selectively dilate arterioles, have no such effect on veins, do not cause postural hypotension, and have no significant inhibitory effect on the myocardium. While reducing renal vascular resistance, it does not affect the glomerular filtration rate and creatinine clearance rate, and the renal blood flow remains unchanged or even slightly increases, and has a natriuretic and diuretic effect. It can increase output and cardiac index, significantly reduce afterload, and has no significant effect on cardiac contractile function, preload, and heart rate. More |
86189-69-7 | 30 |
Appearance
This product is white or off-white tablet.
Indication
Used for the treatment of mild to moderate essential hypertension.
Usage and Dosage
Oral: Starting dose 2.5 mg, twice a day, or as directed by a doctor. The usual maintenance dose is 5 mg or 10 mg per day. If necessary, the dose can be further increased, or other antihypertensive drugs can be added.
Adverse Reactions
This product is the same as other calcium antagonists. Some patients may experience flushing, headache, dizziness, palpitations and fatigue. Most of these reactions are dose-dependent and appear temporarily within a short period of time after the dose is increased, and disappear as the application time increases. This product is the same as other dihydropyridine drugs. It can cause dose-related ankle swelling, gums or periodontitis. Patients may experience mild gum swelling after taking the drug, and may also experience rash and itching.
Precautions
It is contraindicated for those who are allergic to this product.
Special Population Medication
Precautions for children: There is limited experience with the use of this product in children. Precautions for pregnancy and lactation: Pregnant women and those who are allergic to this product are prohibited from using this product. Precautions for the elderly: For patients over 65 years old, the plasma clearance rate of felodipine decreases and the blood concentration will increase. If necessary, adjust the dosage according to the doctor's advice and carefully observe the changes in blood pressure.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
5mg
Validity Period
24 months
Manufacturer
Hunan Dekang Pharmaceutical Co., Ltd.
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Founded in:
1993-07-08 -
Address:
No. 17, Jinzhou Avenue, Changsha High-tech Zone -
Tax NO.:
91430000616776798K -
Registered Funds:
31.8 million yuan -
Website:
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Email: