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Mitiglinide Calcium Tablets

Function and Efficacy

Mitiglinide binds to the sulfonylurea receptors on the pancreatic β-cell membrane, inhibiting the ATP-sensitive K channels on the pancreatic β-cell membrane, causing cell depolarization and increased intracellular Ca2 concentration, thereby promoting insulin secretion and lowering blood sugar.

Ingredients

Mitiglinide calcium. Chemical name: bis[2-(S)-benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid] monocalcium salt dihydrate.

Name Description Content CAS NO. Manufacturer
Mitiglinide calcium dihydrateIngredients

Mitiglinide binds to the sulfonylurea receptors on the pancreatic β-cell membrane, inhibiting the ATP-sensitive K channels on the pancreatic β-cell membrane, causing cell depolarization and increased intracellular Ca2 concentration, thereby promoting insulin secretion and lowering blood sugar.

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207844-01-7 8

Appearance

This product is white or off-white tablets.

Indication

It can improve the changes in blood sugar after eating in patients with type 2 diabetes, and is used for diabetic patients who have not been effectively treated with food therapy and exercise therapy.

Usage and Dosage

Adults should take 10 mg of mitiglinide calcium tablets orally once before each meal (within 5 minutes), 3 times a day. In addition, the dosage can be increased or decreased according to symptoms.

Adverse Reactions

Symptoms of hypoglycemia (5.6%), as well as digestive system symptoms such as abdominal distension (1.4%), constipation (1.1%), diarrhea 1.1%), and hunger 1.1%).

Precautions

1. It is contraindicated for patients with severe ketosis, diabetic lethargy and pre-lethargy, and type 1 diabetes; 2. It is contraindicated for patients with severe infection, before and after surgery, and with critical trauma; 3. It is contraindicated for patients with a history of allergy to the ingredients of this drug; 4. It is contraindicated for pregnant women and women who may become pregnant.

Special Population Medication

Precautions for children: The safety of this product in children has not been established. Precautions for pregnancy and lactation: Pregnant women and women who may become pregnant are prohibited. Precautions for the elderly: Elderly patients usually have low physiological functions. They should start with a low dose (5 mg each time) according to symptoms and pay attention to monitoring blood sugar levels and administer the drug with caution.

Drug Interactions

Caution should be exercised when using mitiglinide calcium in combination with the following drugs. Pay attention to monitoring blood sugar levels and reduce or increase the dosage if necessary.

Storage

Seal and store in a dry place

Packaging Specification

10mg (calculated as C38H48CaN2O6)

Validity Period

24 months

Manufacturer

Jiangsu Hansoh Pharmaceutical Group Co., Ltd.

  • Founded in:

    1995-07-26
  • Address:

    Lianyungang Economic and Technological Development Zone, Jiangsu Province
  • Tax NO.:

    913207006083959289
  • Registered Funds:

    1,000,000,000 Yuan
  • Website:

  • Email:

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