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Licorice Tablets

Function and Efficacy

1. Anti-inflammatory effect (1) Anti-allergic effect Glycyrrhizin has anti-allergic effects such as inhibiting local allergic necrosis reaction (Arthus Phenomenon) and inhibiting Schwartzman phenomenon (Shwartzman Phenomenon) in rabbits. For corticosteroids, it enhances the hormone's inhibitory effect on stress response and antagonizes the hormone's anti-granulation and thymic atrophy effects. It has no effect on the exudation of hormones. (2) Inhibitory effect on arachidonic acid metabolic enzymes Glycyrrhizin can directly bind to phospholipase A2, the initiator enzyme of the arachidonic acid metabolic pathway, and to lipoxygenase, which acts on arachidonic acid to produce inflammatory mediators, selectively inhibiting the phosphorylation of these enzymes and inhibiting their activation. 2. Immunomodulatory effect In vitro tests (invitro) show the following immunomodulatory effects: (1) Regulation of T cell activation; (2) Induction of interferon g; (3) Activation of NK cells; (4) Promotion of extrathymic T lymphocyte differentiation. 3. Inhibition of experimental hepatocyte damage In the rat hepatocyte cell line cultured in vitro, glycyrrhizin inhibited hepatocyte damage caused by carbon tetrachloride. 4. Inhibition of viral proliferation and inactivation of viruses In the mouse MHV (mouse hepatitis virus) infection experiment, administration of glycyrrhizin can prolong the number of days of survival. In the rabbit vaccinia virus (Vacciniavirus) pox prevention experiment, it has an effect of preventing pox; in the in vitro experimental system, the proliferation of herpes viruses and the inactivation of viruses were also observed. Glycine and cysteine hydrochloride can inhibit or alleviate the pseudoaldosterone symptoms caused by electrolyte metabolism abnormalities that may occur due to the long-term use of glycyrrhizin in large quantities.

Ingredients

Glycyrrhizic acid monopotassium salt.

Name Description Content CAS NO. Manufacturer
Monopotassium glycyrrhizateIngredients

1. Anti-inflammatory effects: (1) Anti-allergic effects, inhibiting local allergic necrosis and Schwartzman phenomenon, enhancing the inhibitory effect of hormones on stress response, antagonizing the anti-granulation and thymic atrophy effects of hormones; (2) Inhibiting the activity of arachidonic acid metabolic enzymes, selectively inhibiting the phosphorylation of phospholipase A2 and lipoxygenase and inhibiting their activation. 2. Immunomodulatory effects: (1) Regulating T cell activation; (2) Inducing interferon; (3) Activating NK cells; (4) Promoting the differentiation of extrathymic T lymphocytes. 3. Inhibiting experimental liver cell damage: Inhibiting liver cell damage caused by carbon tetrachloride. 4. Inhibiting virus proliferation and inactivating viruses: Prolonging the survival days of mice infected with hepatitis virus, preventing the formation of pox in rabbits with cowpox virus, inhibiting the proliferation of herpes viruses and inactivating viruses.

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42294-03-1 2

Appearance

This product is a film-coated tablet, which is light brown after removing the film coating; it tastes sweet.

Usage and Dosage

Oral administration: 1 tablet (150 mg) at a time, 2 times a day (300 mg).

Adverse Reactions

A small number of patients experience dizziness, nausea, chest tightness, dry mouth, fatigue, rash and low fever during use. Mild symptoms can be relieved or disappear in a short period of time without treatment; severe symptoms require immediate medical attention. Some patients may experience hypokalemia and high blood pressure. Very few patients experience mild facial or lower limb edema after long-term use, and very few patients experience hyperplasia of body hair.

Precautions

It is contraindicated for those with allergic constitution or allergic to the ingredients of this product.

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

Sealed. Validity period: 2 years.

Packaging Specification

Each tablet contains 75 mg of monopotassium glycyrrhizinate

Validity Period

36 months.

Manufacturer

Fushuitang Pharmaceutical Co., Ltd.

  • Founded in:

    2004-04-30
  • Address:

    Fushoutang Building, Xunda Avenue, High-tech Zone, Xiangtan City
  • Tax NO.:

    91430300760732802H
  • Registered Funds:

    50 million yuan
  • Website:

  • Email:

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