Licorice Tablets
Function and Efficacy
1. Anti-inflammatory effect (1) Anti-allergic effect Glycyrrhizin has anti-allergic effects such as inhibiting local allergic necrosis reaction (Arthus Phenomenon) and inhibiting Schwartzman phenomenon (Shwartzman Phenomenon) in rabbits. For corticosteroids, it enhances the hormone's inhibitory effect on stress response and antagonizes the hormone's anti-granulation and thymic atrophy effects. It has no effect on the exudation of hormones. (2) Inhibitory effect on arachidonic acid metabolic enzymes Glycyrrhizin can directly bind to phospholipase A2, the initiator enzyme of the arachidonic acid metabolic pathway, and to lipoxygenase, which acts on arachidonic acid to produce inflammatory mediators, selectively inhibiting the phosphorylation of these enzymes and inhibiting their activation. 2. Immunomodulatory effect In vitro tests (invitro) show the following immunomodulatory effects: (1) Regulation of T cell activation; (2) Induction of interferon g; (3) Activation of NK cells; (4) Promotion of extrathymic T lymphocyte differentiation. 3. Inhibition of experimental hepatocyte damage In the rat hepatocyte cell line cultured in vitro, glycyrrhizin inhibited hepatocyte damage caused by carbon tetrachloride. 4. Inhibition of viral proliferation and inactivation of viruses In the mouse MHV (mouse hepatitis virus) infection experiment, administration of glycyrrhizin can prolong the number of days of survival. In the rabbit vaccinia virus (Vacciniavirus) pox prevention experiment, it has an effect of preventing pox; in the in vitro experimental system, the proliferation of herpes viruses and the inactivation of viruses were also observed. Glycine and cysteine hydrochloride can inhibit or alleviate the pseudoaldosterone symptoms caused by electrolyte metabolism abnormalities that may occur due to the long-term use of glycyrrhizin in large quantities.
Ingredients
Glycyrrhizic acid monopotassium salt.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Monopotassium glycyrrhizateIngredients |
1. Anti-inflammatory effects: (1) Anti-allergic effects. Glycyrrhizin can inhibit the local allergic necrosis reaction and Schwartzman phenomenon in rabbits. It can enhance the inhibitory effect of corticosteroids on stress response and antagonize the anti-granulation and thymic atrophy effects of hormones. (2) Inhibitory effect on arachidonic acid metabolic enzymes. Glycyrrhizin can selectively inhibit the phosphorylation of these enzymes and inhibit their activation. 2. Immunomodulatory effects: (1) Regulatory effect on T cell activation; (2) Inducing effect on gamma interferon; (3) Activating NK cells; (4) Promoting the differentiation of extrathymic T lymphocytes. 3. Inhibitory effect on experimental hepatocyte damage: Glycyrrhizin inhibits hepatocyte damage caused by carbon tetrachloride in in vitro experiments. 4. Inhibit virus proliferation and inactivate viruses: Glycyrrhizin can prolong the survival days of mice infected with mouse hepatitis virus, and has an effect of preventing acne in rabbit cowpox virus pox prevention experiments. In vitro experiments have been observed to inhibit the proliferation of herpes viruses and inactivate viruses. More |
42294-03-1 | 2 |
Appearance
This product is a film-coated tablet, which is light brown after removing the film coating; it tastes sweet.
Usage and Dosage
Oral administration: 1 tablet (150 mg) at a time, 2 times a day (300 mg).
Adverse Reactions
A small number of patients experience dizziness, nausea, chest tightness, dry mouth, fatigue, rash and low fever during use. Mild symptoms can be relieved or disappear in a short period of time without treatment; severe symptoms require immediate medical attention. Some patients may experience hypokalemia and high blood pressure. Very few patients experience mild facial or lower limb edema after long-term use, and very few patients experience hyperplasia of body hair.
Precautions
It is contraindicated for those with allergic constitution or allergic to the ingredients of this product.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
Sealed. Validity period: 2 years.
Packaging Specification
Each tablet contains 75 mg of monopotassium glycyrrhizinate
Validity Period
36 months.
Manufacturer
Guangzhou Baiyunshan Huacheng Pharmaceutical Co., Ltd.
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Founded in:
1986-04-17 -
Address:
No. 48, Fotian North Road, Jiufo Street, Huangpu District, Guangzhou -
Tax NO.:
91440101MA59BH7X51 -
Registered Funds:
12.7893 million yuan -
Website:
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Email: