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Lobeline Hydrochloride Injection

Function and Efficacy

Literature reports that it can stimulate the carotid sinus and aortic body chemoreceptors (both are N1 receptors), reflexively excite the respiratory center and speed up breathing, but it has no direct excitatory effect on the respiratory center. It also has a reflex excitatory effect on the vagus nerve center and vasomotor center; it first excites the autonomic ganglia and then blocks them.

Ingredients

Lobeline hydrochloride.

Name Description Content CAS NO. Manufacturer
alpha-Lobeline hydrochlorideIngredients

It stimulates the carotid sinus and aortic body chemoreceptors (both N1 receptors), reflexively excites the respiratory center and speeds up breathing, but has no direct excitatory effect on the respiratory center. It also has a reflex excitatory effect on the vagus nerve center and vasomotor center; it first excites the autonomic ganglia and then blocks them.

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Appearance

This product is a colorless or almost colorless clear liquid.

Indication

This product is mainly used for central respiratory depression caused by various reasons. It is commonly used clinically for neonatal asphyxia, carbon monoxide, opioid poisoning, etc.

Usage and Dosage

1. Intravenous injection: Common dosage: 3 mg (1 vial) for adults; Maximum dosage: 6 mg (2 vials) for one time, 20 mg a day. 0.3-3 mg for children, can be repeated every 30 minutes if necessary; 3 mg (1 vial) can be injected into the umbilical vein in case of neonatal asphyxia. 2. Subcutaneous or intramuscular injection: Common dosage: 10 mg for adults; Maximum dosage: 20 mg for one time, 50 mg a day. 1-3 mg for children.

Adverse Reactions

There may be nausea, vomiting, choking, headache, palpitations, etc.

Precautions

Not yet clear.

Special Population Medication

Precautions for children: It can be used for infants and newborns. Precautions for pregnancy and lactation: This experiment has not been conducted and there is no reliable reference. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.

Drug Interactions

This experiment has not been conducted and there are no reliable references.

Storage

Keep away from light and store in airtight container.

Packaging Specification

1ml:3mg

Validity Period

36 months

Manufacturer

China Resources Double-Crane Pharmaceutical Co., Ltd.

  • Founded in:

    1997-05-16
  • Address:

    No. 1, Lize East 2nd Road, Wangjing, Chaoyang District, Beijing
  • Tax NO.:

    91110000633796475U
  • Registered Funds:

    1,038,836,522 yuan
  • Website:

  • Email:

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