Alprostadil for injection

This product is an intravenous alprostadil preparation with lipid microspheres as drug carriers. Due to the encapsulation of lipid microspheres, alprostadil is not easy to be inactivated. In addition, this product has the targeting characteristics of being easily distributed to damaged blood vessels, thereby exerting the effects of this product in dilating blood vessels and inhibiting platelet aggregation.

Chemical name: (1R, 2R, 3R)-3-hydroxy-2[(E)-(3S)-3-hydroxy-1-octenyl]-5-oxocyclopentaneheptanoic acid

This product is white powder or freeze-dried cake.

Used for myocardial infarction, thromboangiitis obliterans, occlusive arteriosclerosis and other diseases.

Dissolve in 250ml or 500ml 0.9% sodium chloride injection or 6% dextran 40 glucose injection, 5% glucose solution, and drip intravenously. The daily dose for myocardial infarction is 100-200μg, which can be increased appropriately for severe cases, but should not exceed 400μg. For thromboangiitis vasculitis and occlusive arteriosclerosis, the daily dose is 100-200μg.

1. Shock: Shock may occur occasionally. Please pay attention to observation. If any abnormality is found, stop the drug immediately and take appropriate measures. 2. Injection site: Sometimes there may be pain and redness in the blood vessels, and sometimes hardness and itching. 3. Circulatory system: Sometimes there may be worsening of heart failure, pulmonary edema, chest tightness, and decreased blood pressure. If these symptoms occur, stop the drug immediately. In addition, redness and vasculitis may occur occasionally, and facial flushing and palpitations may occur occasionally. 4. Digestive system: Sometimes there may be diarrhea, abdominal distension, and discomfort, and occasionally abdominal pain, loss of appetite, vomiting, and constipation. 5. Liver: Occasionally there may be abnormal liver function such as increased GOT and GPT. 6. Mental and nervous system: Sometimes there may be dizziness, headache, fever, fatigue, and occasionally numbness. 7. Skin: Sometimes there may be rash or itching, and occasionally there may be urticaria. 8. Blood system: Occasionally there may be an increase in eosinophils and a decrease in leukocytes. 9. Others: Occasionally there may be decreased vision, swelling in the mouth, hair loss, pain in the limbs, edema, fever, and discomfort.

1. Patients with severe heart failure (heart failure). 2. Women who are pregnant or may become pregnant. 3. Patients with a history of allergic reaction to this preparation.

Pregnancy and lactation precautions: Women who are pregnant or may become pregnant.

This product can increase the effects of antihypertensive drugs and platelet aggregation inhibitors.

Sealed, light-proof, and stored in a cool place. Valid for two years.

20 μg

Nanyang Pukang Pharmaceutical Co., Ltd.

• Founded in:

  2008-02-22

• Address:

  No. 143, Gongye Road, Nanyang City, Henan Province

• Tax NO.:

  91411300176354654C

• Registered Funds:

  132 million yuan

• Website:

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• Email:

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