Compound Amino Acid Injection for Children (18AA-Ⅰ)
Function and Efficacy
Amino acids are the basic units that make up human proteins and enzymes, and are the raw materials for synthesizing hormones. They participate in human metabolism and various physiological functions, and play an extraordinary role in life. Amino acids have different metabolic effects in infants and adults. The activity of phenylalanine hydroxylase in infants is low, which can easily lead to hyperphenylalaninemia. Because of the low activity of cystathionase, hypermethioninemia is easy to occur. The synthesis rate of histidine is slow, which can easily lead to hypohistidinemia. Therefore, the dosage of phenylalanine, methionine, and glycine should be reduced for amino acid infusion for infants and young children, and the dosage of cysteine, tyrosine, and histidine should be increased, so that the plasma amino acid spectrum can remain normal. This product adapts to the metabolic characteristics of infants and young children, reduces the dosage of phenylalanine, methionine, and glycine, increases the dosage of cysteine and histidine, and meets the nutritional needs of children.
Ingredients
It is composed of 18 kinds of amino acids, and the amino acid content is 6.74% (calculated as salt). L-isoleucine, L-alanine, L-leucine, L-proline, L-lysine, L-arginine (L-lysine acetate), L-serine, L-methionine, L-aspartic acid, L-phenylalanine, L-glutamic acid, L-threonine, glycine, L-tryptophan, L-tyrosine, L-valine, etc. Absorption, distribution, elimination: On the one hand, the tissue protein of the human body is decomposed into amino acids, and on the other hand, it is synthesized from amino acids. It is a continuous decomposition and synthesis to maintain a dynamic balance. The amino acid conversion is very rapid and frequent. The twenty kinds of amino acids that make up protein have common groups-amino and carboxyl groups, so they have similar metabolic processes. They all need to deaminate to generate ammonia and alpha-keto acid. Ammonia and carbon dioxide generate urea, which is excreted through the kidneys. Alpha-keto acid can provide energy, generate water and carbon dioxide for excretion, and can also be converted into sugar or fat.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| L-IsoleucineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
73-32-5 | 20 | |
| L-AlanineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
56-41-7 | 8 | |
| L-LeucineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
61-90-5 | 11 | |
| L-ProlineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
147-85-3 | 13 | |
| L-LysineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
6899-06-5 | 0 | |
| L-SerineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
56-45-1 | 10 | |
| L-MethionineIngredients |
Infants and young children have low cystathionase activity and are prone to hypermethioninemia; therefore, this product reduces the amount of methionine to adapt to the metabolic characteristics of infants and young children. More |
63-68-3 | 12 | |
| L-Aspartic acidIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
56-84-8 | 1 | |
| L-PhenylalanineIngredients |
Infants and young children have low phenylalanine hydroxylase activity and are prone to hyperphenylalaninemia; therefore, this product reduces the dosage of phenylalanine to adapt to the metabolic characteristics of infants and young children. More |
3617-44-5 | 0 | |
| L-Glutamic acidIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
56-86-0 | 18 | |
| L-ThreonineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
72-19-5 | 13 | |
| GlycineIngredients |
The dosage of glycine should be reduced in amino acid infusion for infants and young children to adapt to their metabolic characteristics. More |
56-40-6 | 27 | |
| L-TryptophanIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
73-22-3 | 12 | |
| L-TyrosineIngredients |
Increase the amount of tyrosine to meet the nutritional needs of children. More |
60-18-4 | 7 | |
| L-ValineIngredients |
Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions. More |
72-18-4 | 9 | |
| L-CysteineIngredients |
Increase the amount of cysteine to adapt to the metabolic characteristics of infants and young children. More |
52-90-4 | 6 | |
| L-HistidineIngredients |
The synthesis rate of histidine in infants and young children is slow, which can easily lead to hypohistidinemia; therefore, the dosage of histidine should be increased to adapt to the metabolic characteristics of infants and young children. More |
71-00-1 | 20 | |
| L(+)-ArginineIngredients |
Participates in human metabolism and various physiological functions, and is the basic unit of human proteins and enzymes. More |
74-79-3 | 25 | |
| L-HistidineIngredients |
The synthesis rate of histidine in infants and young children is slow, which can easily lead to hypohistidinemia. This product is adapted to the metabolic characteristics of infants and young children and increases the dosage of histidine. More |
71-00-1 | 20 |
Indication
Children with digestive system diseases, hypoproteinemia caused by various diseases, severe trauma, burns, sepsis and other nitrogen imbalances in the body, refractory diarrhea, malabsorption syndrome, parenteral nutrition for premature infants and low birth weight infants.
Usage and Dosage
1 When used for a long time through the central vein, it should be used in combination with hypertonic glucose (or glucose and fat emulsion), electrolytes, vitamins, trace elements, etc., in order to achieve the purpose of nutritional support. 2 When used through the peripheral vein, it can be diluted with 10% glucose injection and slowly dripped. 3 Infusion rate: When the peripheral vein is fully infused, the full-day dosage should be not less than 16 hours after the liquid is diluted, and dripped evenly. For partial intravenous nutrition infusion and central vein infusion, follow the doctor's advice. 4 The infusion volume should be determined according to the child's age, weight, condition, etc. The general dosage is 15ml/kg/day of amino acids at the beginning (equivalent to about 1g of amino acids), and then increased to 39ml/kg/day (equivalent to 2.5g of amino acids). At the end of the treatment, attention should be paid to gradually reducing the dosage to prevent hypoglycemia.
Adverse Reactions
When this product is infused quickly, it is easy to cause increased heart rate, gastrointestinal reactions and fever.
Precautions
1. Children with liver and kidney damage. 2. Children with amino acid metabolism disorders.
Drug Interactions
Not yet clear.
Storage
Store in a cool, dark place.
Packaging Specification
100ml:6.74g (total amino acids)
Manufacturer
Hubei Jinyao Pharmaceutical Co., Ltd.
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Founded in:
2001-04-16 -
Address:
No. 99, Hanjiang North Road, Xiangyang City, Hubei -
Tax NO.:
914206001793185603 -
Registered Funds:
108.47299 million yuan -
Website:
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Email: