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L-Arginine

L-Arginine structure

CAS No:
74-79-3
Formula:
C6H14N4O2
Chemical Name:
L-Arginine
Synonyms:
L-Arginine;Arginine,L-;Arginine;Pentanoic acid,2-amino-5-[(aminoiminomethyl)amino]-,(S)-;L-(+)-Arginine;(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid;L-Norvaline,5-[(aminoiminomethyl)amino]-;L-Ornithine,N5-(aminoiminomethyl)-;L-α-Amino-δ-guanidinovaleric acid;L-Arg;NSC 206269;L-arginine C Grade;A 0526;(2S)-2-Amino-5-(diaminomethylideneamino)pentanoic acid;42: PN: WO2020027640 SEQID: 105 claimed protein;42: PN: KR20200014684 SEQID: 105 claimed sequence;117: PN: WO2021061872 SEQID: 117 claimed protein;142-49-4;7004-12-8;154605-63-7;154605-67-1;667422-95-9;1332377-47-5
Categories:
Cosmetic Ingredient > Antistatic

Description

L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.Target: OthersL-Arginine is an α-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synth

Solid

L-Arginine Basic Attributes

Molecular Weight：

174.2

Exact Mass：

174.20

BRN：

1725413

EC Number：

200-811-1

HScode：

29252000

Characteristics

PSA：

128

XLogP3：

-4.2

Appearance：

white powder

Density：

1.10 g/cm³

Melting Point：

244 °C

Boiling Point：

409.1°C at 760 mmHg

Flash Point：

176.1±30.7 °C

Refractive Index：

1.601

Water Solubility：

H2O: 148.7 g/L (20 ºC)

Storage Conditions：

Storeat0-5

Toxicity：

Reference value: peritoneal-rat LD50: 3793 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxide fumes

Specific rotation：

27.1 º (c=8, 6N HCl)

PH：

Strongly alkaline

PKA：

2.24(at 0 °C)

Safety Information

Hazard category：

IRRITANT

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36-36/37/38-20/21/22-61

safety instructions：

24/25-36-26-45-53-39

RTECS Number：

CF1934200

Marks：

Xn,T

Storage features：

Warehouse ventilated, low temperature and dry

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Precautionary statement(s)：

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

Hazard Statements：

H315

Toxicity

Toxicity class：

moderately toxic

L-Arginine Use and Manufacturing

Methods of Manufacturing

Gelatin is used as raw material, hydrochloric acid hydrolyzed and then condensed with benzaldehyde to obtain benzylidene arginine, and the finished product is obtained by hydrochloric acid hydrolysis, activated carbon treatment, and column chromatography.

Uses

Nitric oxide synthase substrate can be converted to citrulline and NO. Induces insulin secretion by a mechanism that depends on NO.Used as pharmaceutical raw materials and food additives. Nutritional supplements; flavoring agents. For biochemical research, various types of hepatic coma and viral hepatic alanine aminotransferase abnormalities

Computed Properties

Molecular Weight:174.20
XLogP3:-3.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:174.11167570
Monoisotopic Mass:174.11167570
Topological Polar Surface Area:132
Heavy Atom Count:12
Complexity:171
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Barium hydroxide

Drug Function and Efficacy

Amino acids are the basic units that make up human proteins and enzymes. They are the raw materials for synthesizing hormones, participate in human metabolism and various physiological functions, and play a special role in life.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Amino Acid Injection (15AA)
Ingredients	This product is a compound preparation, and its components are as follows: Each 1000ml contains L-isoleucine 7.66g L-valine 8.86g L-leucine 13.78g L-alanine 4g L-lysine 4.1g L-arginine 5.8g (lysine acetate 5.8g) L-histidine 1.6g methionine 2.50g L-serine 3.3g L-phenylalanine 3.20g L-proline 6.3g L-threonine 2g glycine 3.3g<br/
Indication	Not yet clear.
Specifications	100 ml: 8 g (total amino acids)
Manufacturer	Chengdu Brilliant Pharmaceutical Co., Ltd.

Compound Amino Acid Injection (18AA)
Ingredients	The main ingredients of this product are: 18 kinds of amino acids. The amino acid content is 10%. Amino acid concentration (mg/1000ml) L-isoleucine 560 L-arginine 790 L-leucine 1,250 L-aspartic acid 380 acetate L-lysine 1,240 L-cysteine 100 (equivalent to lysine 880) L-glutamic acid 650 L-methionine 350 L-histidine 600 L-phenylalanine 935 L-proline 330 L-threonine 650 L-serine 220 L-tryptophan
Indication	Not yet clear.
Specifications	500ml:25g(total amino acids)
Manufacturer	Zhejiang Guojing Pharmaceutical Co., Ltd.

Compound Amino Acid Injection (18AA)
Ingredients	The main ingredients of this product are: 18 kinds of amino acids. The amino acid content is 10%. Amino acid concentration (mg/1000ml) L-isoleucine 560 L-arginine 790 L-leucine 1,250 L-aspartic acid 380 acetate L-lysine 1,240 L-cysteine 100 (equivalent to lysine 880) L-glutamic acid 650 L-methionine 350 L-histidine 600 L-phenylalanine 935 L-proline 330 L-threonine 650 L-serine 220 L-tryptophan
Indication	Not yet clear.
Specifications	250m1:30g (total amino acids)
Manufacturer	Hubei Changlian Dule Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

AJINOMOTO CO., INC

Pakistan
Active
Shanghai Primano Amino Acid Co., Ltd.

China
Active
Jinyao Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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Arginine 98.5% White crystalline powder Dongxiao Brand

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Guide of L-Arginine

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Use and Manufacturing
Computed Properties
Material
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

L-Arginine

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