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Acyclovir eye drops

Function and Efficacy

This product is a nucleoside antiviral drug that has a selective inhibitory effect on a variety of herpes viruses (HSV). After acyclovir enters HSV-infected cells, it binds to the specific thymidylate kinase encoded by the virus and is rapidly converted into acyclosine monophosphate, which is then converted into acyclosine diphosphate by the cell's guanylate kinase. It is then converted into acyclosine triphosphate by other cell enzymes, and competes with guanylate triphosphate to infect herpes simplex virus DNA polymerase, thereby inhibiting viral DNA synthesis. Acyclovir triphosphate is a very strong viral DNA polymerase inhibitor, and has an inhibitory effect on the DNA polymerases of five human herpes viruses, namely HSV-1, HSV-2, VZV, CMZ and EBV. It has no effect on normal cells, and its antiviral efficacy is 160 times stronger than that of adenosine.

Ingredients

The main ingredient of this product is acyclovir, and its chemical name is: 9-[(2-hydroxyethoxy)methyl]guanine

Name Description Content CAS NO. Manufacturer
AcyclovirIngredients

This product is a nucleoside antiviral drug that has a selective inhibitory effect on a variety of herpes viruses (HSV). After acyclovir enters HSV-infected cells, it binds to the specific thymidylate kinase encoded by the virus and is rapidly converted into acyclosine monophosphate, which is then converted into acyclosine diphosphate by the cell guanylate kinase, and then converted into acyclosine triphosphate by other cell enzymes, and competes with guanylate triphosphate to infect herpes simplex virus DNA polymerase, thereby inhibiting viral DNA synthesis. Acyclovir triphosphate is a strong viral DNA polymerase inhibitor, which has an inhibitory effect on the DNA polymerase of five human herpes viruses, namely HSV-1, HSV-2, VZV, CMZ and EBV, and has no effect on normal cells. Its antiviral efficacy is 160 times stronger than that of adenosine.

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59277-89-3 50

Appearance

This product is a colorless, clear solution.

Indication

This product is mainly used to treat herpes simplex keratitis.

Usage and Dosage

Place 1-2 drops into the eyelids, once every 2 hours.

Adverse Reactions

This product is generally well tolerated after eye drops. The adverse reactions it may cause include burning irritation, conjunctival congestion, superficial punctate keratopathy, follicular conjunctivitis, eyelid allergy and lacrimal punctum obstruction, etc., and the incidence rate is generally low.

Precautions

1. Those who are allergic to this product or have serious complications are prohibited from using it. 2. Pregnant and lactating women should use it with caution.

Special Population Medication

Precautions during pregnancy and lactation: Use with caution in pregnant and lactating women

Drug Interactions

This product competitively inhibits the secretion of organic acids with probenecid. The combined use of probenecid can slow down the excretion of this product, prolong its half-life, and accumulate the amount of drug in the body.

Storage

Seal tightly and store in a cool, dark place.

Packaging Specification

8ml:8mg

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