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Cyclic Adenosine Monophosphate for Injection

Function and Efficacy

It is a protein kinase activator and a derivative of nucleotides. It is an important substance with physiological activity that is widely present in the human body. It is produced by adenosine triphosphate under the catalysis of adenylate cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological functions and material metabolism in cells, can change the function of cell membranes, promote calcium ions in reticulum to enter muscle fibers, thereby enhancing myocardial contraction, and can promote the activity of respiratory chain oxidases, improve myocardial hypoxia, relieve symptoms of coronary heart disease and improve electrocardiograms. In addition, it plays an important role in regulating sugar, fat metabolism, nucleic acid, and protein synthesis.

Ingredients

Cyclic AMP

Name Description Content CAS NO. Manufacturer
Cyclic AMPIngredients

It is a protein kinase activator and a derivative of nucleotides. It is an important substance with physiological activity that is widely present in the human body. It is produced by adenosine triphosphate under the catalysis of adenylate cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological functions and material metabolism in cells, can change the function of cell membranes, promote calcium ions in reticulum to enter muscle fibers, thereby enhancing myocardial contraction, and can promote the activity of respiratory chain oxidases, improve myocardial hypoxia, relieve symptoms of coronary heart disease and improve electrocardiograms. In addition, it plays an important role in regulating sugar, fat metabolism, nucleic acid, and protein synthesis.

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Indication

It is used for angina pectoris, myocardial infarction, myocarditis and cardiogenic shock. It has a certain effect on improving the symptoms of palpitations, shortness of breath and chest tightness in rheumatic heart disease. It can improve the efficacy of acute leukemia combined with chemotherapy and can also be used for induction remission of acute leukemia. In addition, it also has a certain effect on chronic bronchitis in the elderly, various hepatitis and psoriasis.

Usage and Dosage

Intramuscular injection, 20 mg at a time, dissolved in 2 ml 0.9% sodium chloride injection, twice a day. Intravenous injection, 20 mg at a time, dissolved in 20 ml 0.9% sodium chloride injection, bolus injection, twice a day. Intravenous drip, 40 mg of this product dissolved in 250-500 ml 5% glucose injection, once a day. Coronary heart disease is treated for 15 days, and can be used continuously for 2-3 courses; leukemia is treated for one month; psoriasis is treated for 2-3 weeks, which can be extended to 4-7 weeks, and the daily dosage can be increased to 60-80 mg.

Adverse Reactions

Fever and rash are occasionally seen. Large doses of intravenous injection (up to 0.5 mg/kg per minute based on body weight) can cause abdominal pain, headache, myalgia, testicular pain, back pain, limb weakness, nausea, numbness of hands and feet, high fever, etc.

Precautions

Not yet clear.

Drug Interactions

Not yet clear.

Storage

Seal tightly or melt seal and store in a cool place.

Packaging Specification

40mg

Manufacturer

Guangzhou Yipinhong Pharmaceutical Co., Ltd.

  • Founded in:

    2010-07-16
  • Address:

    No. 6 Dongbo Road, East District, Guangzhou Economic and Technological Development Zone
  • Tax NO.:

    914401015583834183
  • Registered Funds:

    50 million yuan
  • Website:

  • Email:

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