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Miconazole clobetasol cream

Function and Efficacy

This product is a compound preparation of miconazole nitrate and clobetasol propionate. Miconazole nitrate is an imidazole antifungal drug. It has antibacterial effect and can also be bactericidal at high concentrations; it can inhibit the biosynthesis of fungal ergosterol and other sterols; it acts on the fungal cell membrane, damages the fungal cell membrane and changes its permeability, causing the leakage of important substances in the cell; it can also inhibit the biosynthesis of fungal triglycerides and phospholipids: it can also inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxides in the cell, leading to degeneration or necrosis of fungal subcellular structures; it can inhibit the transformation of Candida albicans spores into invasive hyphae. Clobetasol propionate is a highly effective topical corticosteroid with capillary constriction and anti-inflammatory effects.

Ingredients

This product is a compound preparation, its components are miconazole nitrate, clobetasol propionate, etc.

Name Description Content CAS NO. Manufacturer
Miconazole nitrateIngredients

Imidazole antifungal drugs have antibacterial or bactericidal effects. They can inhibit the biosynthesis of fungal ergosterol and other sterols, damage the fungal cell membrane and change its permeability, resulting in the leakage of important intracellular substances; they can inhibit the biosynthesis of fungal triglycerides and phospholipids; they can also inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxides in the cell, leading to degeneration or necrosis of the fungal subcellular structure; for Candida albicans, they can inhibit the transformation of its spores into invasive hyphae.

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22832-87-7 31
Clobetasol propionateIngredients

A highly potent topical corticosteroid with capillary constriction and anti-inflammatory effects.

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25122-46-7 27

Appearance

This product is a milky white ointment with an emulsion base.

Indication

Used for dermatitis, eczema, tinea manuum, tinea cruris and allergic dermatitis caused by fungi

Usage and Dosage

For external use, apply evenly to the affected area 1-2 times a day.

Adverse Reactions

The medication site may produce irritation symptoms such as blisters, erythema, congestion, burning, itching, folliculitis, skin atrophy and thinning, capillary dilation; it may also cause dry skin, hirsutism, atrophic striae, increased susceptibility to infection, etc. Long-term and large-area medication may cause hypercortical syndrome, manifested as hirsutism, acne, moon face, osteoporosis, etc. It may occasionally cause allergic contact dermatitis.

Precautions

1. It is contraindicated for those who are allergic to corticosteroids and imidazoles. 2. It is contraindicated for use on skin folds such as the face, eyes, armpits and groin.

Special Population Medication

Precautions for children: For children, if the drug is used on a large area or for a long time, it will increase the systemic absorption of the drug, so it is not suitable for infants and children. Precautions for pregnancy and lactation: 1. Pregnant and lactating women should use it under the guidance of a physician and weigh the pros and cons. 2. Pregnant women are prohibited from using it for a long time or on a large area. Precautions for the elderly: Elderly patients should use it with caution.

Drug Interactions

Not yet clear.

Storage

Keep in a dark, sealed and cool place

Packaging Specification

2%

Validity Period

36 months

Manufacturer

Shanghai Starry Pharmaceutical Co., Ltd.

  • Founded in:

    2012-06-05
  • Address:

    No. 500, Maoye Road, Jinshan Industrial Zone, Shanghai
  • Tax NO.:

    9131011659810839XL
  • Registered Funds:

    500 million yuan
  • Website:

  • Email:

Other Drugs of Shanghai Starry Pharmaceutical Co., Ltd.

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