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Cefaclor Capsules

Function and Efficacy

Antibacterial drug. The beta-lactamase produced by Staphylococcus aureus is relatively stable, so it has a strong antibacterial effect on Gram-positive bacteria; the beta-lactamase produced by Gram-negative bacteria is unstable, so it has a weaker effect on Gram-negative bacteria and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

Ingredients

The main ingredient of this product is: Cefaclor. Molecular formula: C15H14ClN3O4SH2O Molecular weight: 385.82

Name Description Content CAS NO. Manufacturer
CefaclorIngredients

Antibacterial drug. The beta-lactamase produced by Staphylococcus aureus is relatively stable, so it has a strong antibacterial effect on Gram-positive bacteria; the beta-lactamase produced by Gram-negative bacteria is unstable, so it has a weaker effect on Gram-negative bacteria and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

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53994-73-3 29

Appearance

Capsules, the contents are white to light yellow powder.

Indication

This product is mainly used for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

Oral: The usual adult dose is 0.25g once, 3 times a day. The dose can be doubled for patients with severe infection, but the total daily amount should not exceed 4.0g. Or follow the doctor's advice. Children can take 20-40mg/kg per day according to body weight, divided into 3 doses, but the total daily amount should not exceed 4 capsules or follow the doctor's advice.

Adverse Reactions

1 Gastrointestinal: diarrhea, stomach discomfort, nausea, vomiting, etc. 2 Allergic reactions: urticaria, rash, eosinophilia, vulvar itching. 3 Others: slight increase in aminotransferase, plasma urea nitrogen (BUN) and creatinine (Cr), proteinuria, cystic urine, etc.

Precautions

It is contraindicated in patients allergic to cephalosporins.

Special Population Medication

Precautions for children: The safety of the drug for newborns has not yet been determined. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other antineoplastic drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of beta-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.

Storage

Keep away from light, seal tightly, and store in a cool, dark and dry place.

Packaging Specification

Calculated as C15H14ClN3O4S 0.25 g

Validity Period

24 months

Manufacturer

Shandong Zibo Xinda Pharmaceutical Co., Ltd.

  • Founded in:

    1993-03-11
  • Address:

    No. 1, Lutai Avenue, Zibo High-tech Zone
  • Tax NO.:

    9137030361328152XT
  • Registered Funds:

    84.93 million yuan
  • Website:

  • Email:

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