Amoxicillin Sodium for Injection

Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

The main ingredient of this product is amoxicillin sodium, and its chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(R)-(-)-2-amino-2-(4-hydroxyphenyl)acetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate sodium.

This product is white or off-white powder or crystal.

Amoxicillin is suitable for patients with the following infections caused by sensitive bacteria (non-β-lactamase-producing strains) who are in severe condition and need hospitalization or cannot take oral medication. 1 Upper respiratory tract infections such as otitis media, sinusitis, pharyngitis, tonsillitis, etc. caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 2 Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3 Skin and soft tissue infections caused by hemolytic streptococci, staphylococci or Escherichia coli. 4 Lower respiratory tract infections such as acute bronchitis and pneumonia caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 5nbs

Intramuscular injection or intravenous drip after dilution. Adults take 0.5-1g once, once every 6-8 hours. Children take 50-100mg/kg of body weight per day, divided into 3-4 doses. Patients with severe renal impairment need to adjust the dosage, including 0.25-0.5g every 12 hours for patients with endogenous creatinine clearance of 10-30ml/min; 0.25-0.5g every 24 hours for patients with endogenous creatinine clearance less than 10ml/min. Hemodialysis can remove this product, and 1g of amoxicillin should be given after each hemodialysis.

1 Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2 Allergic reactions such as rash, drug fever and asthma. 3 Anemia, thrombocytopenia, eosinophilia, etc. 4 Serum aminotransferase may be slightly elevated. 5 Superinfection caused by Candida or drug-resistant bacteria. 6 Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.

It is contraindicated in patients with penicillin allergy or penicillin skin test positive.

1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but its clinical significance is unclear.

Keep away from light and store in a sealed container.

1.0g (calculated as C16H19N3O5S)

Gansu Lanyao Pharmaceutical Co., Ltd.

• Founded in:

  2006-12-22

• Address:

  No. 1739, Middle Section of Kunlunshan Avenue, Lanzhou New District, Lanzhou City, Gansu Province

• Tax NO.:

  916200007948829218

• Registered Funds:

  84.5 million yuan

• Email:

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