Acetaminophen Injection

This product is an acetanilide antipyretic analgesic. It inhibits the prostaglandin synthase in the hypothalamic temperature regulation center, reduces the synthesis and release of prostaglandin PGE1, causes peripheral vasodilation and sweating, and achieves an antipyretic effect. Its antipyretic effect is similar to that of aspirin; it inhibits the synthesis and release of prostaglandins PGE1, bradykinin and histamine, increases the pain threshold and plays an analgesic role. It is a peripheral analgesic, weaker than aspirin, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect. Acute toxicity test results: The oral LD50 of mice is 338mg/kg, and the intraperitoneal injection LD50 is 500mg/kg.

Acetaminophen. Its chemical name is N-(4-hydroxyphenyl)acetamide.

This product is a colorless or almost colorless, slightly viscous, clear liquid.

It is used for fever and can also be used to relieve mild to moderate pain, such as headache, muscle pain, joint pain, neuralgia, dysmenorrhea, cancer pain and postoperative analgesia. This product can be used for patients who are allergic to or cannot tolerate aspirin. This product is ineffective for various severe pains and visceral smooth muscle colic.

Intramuscular injection of 0.15g ~ 0.25g. This product should not be used for a long time. The antipyretic course should not exceed 3 days, and the analgesic course should not exceed 10 days.

At conventional doses, acetaminophen has few adverse reactions, and may occasionally cause nausea, vomiting, sweating, abdominal pain, pale skin, etc. In a few cases, allergic dermatitis (rash, itchy skin, etc.), granulocytopenia, thrombocytopenia, anemia, liver damage, etc. may occur, and it rarely causes gastrointestinal bleeding.

It is contraindicated for patients who are allergic to this product or have severe liver and kidney dysfunction.

Precautions for children: Children under 3 years old should avoid using this product due to their underdeveloped liver and kidney functions. This product contains benzyl alcohol and is prohibited for intramuscular injection in children. This product is contained in children's muscles. Precautions for pregnancy and lactation: This product can pass through the placenta, so the adverse effects on the fetus caused by pregnant women using this product should be considered. Although this product can reach a certain concentration in breast milk after lactating women use it, this product or its metabolites have not been found in the urine of breastfeeding infants. It is not recommended for pregnant and lactating women. Precautions for the elderly: Due to the decline of liver and kidney function in elderly patients, the half-life of this product is prolonged, and adverse reactions are prone to occur. It should be used with caution or in a reduced dose.

1. Long-term use of this product by patients who drink or use other liver enzyme inducers, especially barbiturates or anticonvulsants, may increase the risk of liver toxicity. 2. When used in combination with chloramphenicol, this product can prolong the half-life of the latter and enhance its toxicity. 3. When used in combination with anticoagulants, it can enhance the anticoagulant effect, so the dosage of anticoagulants should be adjusted. 4. When used in combination with aspirin and other non-steroidal anti-inflammatory drugs for a long time, there is a significant risk of increased renal toxicity. 5. When used in combination with the antiviral drug Zidovudine, this product can increase its toxicity and should be avoided at the same time.

Keep away from light and store in a sealed container.

2ml:0.25g

24 months

Zhejiang Ruixin Pharmaceutical Co., Ltd.

• Founded in:

  2002-01-08

• Address:

  Development Road, Tianning Industrial Zone, Liandu District, Lishui City, Zhejiang Province

• Tax NO.:

  91330000735259021T

• Registered Funds:

  50 million yuan

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