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Aprotinin for injection

Function and Efficacy

This product is a broad-spectrum protease inhibitor and has an effect on plasmin and the like.

Ingredients

Peptidase inhibitors.

Appearance

This product is white or off-white freeze-dried block or powder, and is soluble in water.

Indication

Used for open heart surgery with extracorporeal circulation or other surgeries. Inhibits fibrinolytic protein, reduces intraoperative and postoperative bleeding and postoperative intestinal adhesion.

Usage and Dosage

1. Allergic reaction test: Before use, dissolve 1 bottle of this product in 10ml of 5% glucose injection, draw out 1ml, dilute it with 5% glucose injection to a solution containing 2500 units (KIU) of aprotinin per 1ml, inject 1ml intravenously, and observe closely for 15 minutes. If an allergic reaction occurs, it cannot be used. 2. Before extracorporeal circulation, add 3 million to 5 million units (KIU) of this product (1.5 million to 2 million units for children) to the priming solution at one time.

Adverse Reactions

Occasionally, nausea, vomiting, diarrhea, etc. may occur. A very small number of patients may experience a transient increase in serum creatinine and allergic and anaphylactic reactions.

Precautions

People who are allergic to aprotinin.

Drug Interactions

1. This product can inhibit the antihypertensive effect of angiotensin converting enzyme inhibitors (such as captopril) (it has been reported, but there is no conclusive opinion yet). 2. This product has the effect of antagonizing plasmin (such as alteplase, anistreplase, streptokinase, urokinase, etc.) and can be used to inhibit bleeding caused by these drugs. 3. This product can interfere with the following tests: blood clotting time, serum creatinine kinase (CK), serum creatinine, aminotransferase, etc.

Storage

Keep in a dark, airtight place and in a cool place

Packaging Specification

28 units

Manufacturer

Jilin Aodong--Taonan Pharnalentical Company Ltd

  • Founded in:

    1998-02-06
  • Address:

    No. 2999, Xingye Road, Taonan Economic Development Zone, Jilin Province
  • Tax NO.:

    912208007022438244
  • Registered Funds:

    70.170757 million yuan
  • Website:

  • Email:

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