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Ampicillin Granules

Function and Efficacy

The antibacterial effect of this product on Gram-positive cocci and bacilli (including anaerobic bacteria) is basically the same as that of penicillin, and its effect on Enterococcus faecalis is stronger than that of penicillin. Among Gram-negative bacteria, Neisseria meningitidis, Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella, Proteus mirabilis, and Salmonella are all sensitive to this product. Some Escherichia coli and some Shigella are also sensitive to this product, but most Shigella are resistant to this product. Other Enterobacteriaceae, Pseudomonas aeruginosa, Bacteroides fragilis, etc. are resistant to this product. This product has a certain antibacterial effect on Legionella and Campylobacter fetus.

Ingredients

The main ingredient of this product is ampicillin.

Name Description Content CAS NO. Manufacturer
AmpicillinIngredients

The antibacterial effect on Gram-positive cocci and bacilli (including anaerobic bacteria) is basically the same as that of penicillin, and the effect on Enterococcus faecalis is stronger than that of penicillin. Among Gram-negative bacteria, Neisseria meningitidis, Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella, Proteus mirabilis, and Salmonella are all sensitive to this product. Some Escherichia coli and some Shigella are also sensitive to this product, but most Shigella are resistant to this product. Other Enterobacteriaceae, Pseudomonas aeruginosa, Bacteroides fragilis, etc. are resistant to this product. This product has a certain antibacterial effect on Legionella and Campylobacter fetus.

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69-53-4 26

Appearance

This product is white or off-white dry suspension or granules.

Indication

It is suitable for respiratory tract infections, urinary tract infections, digestive tract infections, ear, nose and throat infections, skin and soft tissue infections, and gonorrhea caused by sensitive pathogens.

Usage and Dosage

Before taking, rinse with cold boiled water to the 60 ml mark, shake well before each serving, and then pour into a special small cup and take according to the following dosage. Age: Dosage: Daily dosage: 5 ml 3 times for children under 1 year old 10 ml 3 times for children aged 1 to 3 years old 15 ml 3 times for children aged 3 to 5 years old 20 ml 3 times for children aged 5 to 10 years old

Adverse Reactions

1. The adverse reactions of this product are similar to those of penicillin, with allergic reactions being more common. Rash is the most common reaction, which usually occurs 5 days after medication, in the form of urticaria or maculopapular rash; interstitial nephritis may also occur; anaphylactic shock is occasionally seen. 2. Gastrointestinal reactions such as glossitis, gastritis, nausea, vomiting, enteritis, diarrhea, and mild abdominal pain are also common. 3. Granulocytopenia and thrombocytopenia are occasionally seen in patients taking ampicillin. Antibiotic-related enteritis is rare, and a few patients have elevated serum alanine aminotransferase (ALT).

Precautions

1. Use with caution in patients with a history of allergy to penicillin or those with a positive penicillin skin test. 2. Contraindicated in children under 2 years old.

Special Population Medication

Precautions for children: It is forbidden to use in children under 2 years old. Precautions for pregnancy and lactation: There are no strict controlled trials for the use of ampicillin in pregnant women, so pregnant women should use this product only when it is necessary. A small amount of ampicillin can be secreted from breast milk, so breastfeeding should be suspended when breastfeeding women take the drug. Precautions for the elderly: Due to the decline of biological renal function, the dosage should be appropriately reduced.

Drug Interactions

1. Ampicillin and kanamycin have synergistic antibacterial effects against Escherichia coli and Proteus. 2. Ampicillin can stimulate estrogen metabolism or reduce its enterohepatic circulation, thereby reducing the effectiveness of oral contraceptives. 3. Combination with allopurinol can increase the incidence of ampicillin rash, especially in hyperuricemia. 4. When combined with chloramphenicol for bacterial meningitis, the incidence of long-term sequelae is higher than when either is used alone.

Storage

Keep in a cool place.

Packaging Specification

(calculated as C16H19N3O4S) 0.25g

Validity Period

36 months

Manufacturer

Shandong Zibo Xinda Pharmaceutical Co., Ltd.

  • Founded in:

    1993-03-11
  • Address:

    No. 1, Lutai Avenue, Zibo High-tech Zone
  • Tax NO.:

    9137030361328152XT
  • Registered Funds:

    84.93 million yuan
  • Website:

  • Email:

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