Fleroxacin for injection

The mechanism of action of this product is to inhibit the DNA gyrase of bacteria and thus kill bacteria. This product is a broad-spectrum antibacterial drug, and has strong antibacterial effects on Gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, Proteus, Salmonella typhi, Salmonella paratyphi, Shigella, Enterobacter cloacae, Enterobacter aerogenes, Citrobacter, Serratia marcescens, Pseudomonas aeruginosa, Neisseria meningitidis, Haemophilus influenzae, Moracata, Legionella pneumophila, and Neisseria gonorrhoeae. It also has moderate antibacterial effects on Gram-positive bacteria such as Staphylococcus and hemolytic Streptococcus.

The main ingredient of this product is fleroxacin, and its chemical name is 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid. The chemical structure is as follows: Molecular formula: C17H18F3N3O3 Molecular weight: 369.34 Excipients: mannitol, lactic acid.

This product is a slightly yellow loose mass.

This product belongs to the fluoroquinolone antibacterial drug, suitable for moderate to severe respiratory system, urinary system, digestive system and skin and soft tissue infections, sepsis, gynecological infections, etc. caused by sensitive bacteria such as Enterobacteriaceae such as Klebsiella pneumoniae, Proteus Salmonella, Escherichia coli, methicillin-sensitive Staphylococcus and other sensitive bacteria.

Inject slowly into the vein in a dark place. For adults, take 0.2-0.4 g each time. Add to 250 ml of 5% glucose solution and drip intravenously once a day, or as directed by the doctor.

Common adverse reactions are gastrointestinal reactions, such as nausea, vomiting, diarrhea, and constipation; followed by central nervous system reactions, manifested as insomnia, headache, dizziness, irritability, etc. It can also cause skin photosensitivity, phlebitis, rash, skin itching, palpitations, convulsions, disorientation, and hallucinations, most of which are mild.

It is contraindicated for patients who are allergic to this product or quinolones, pregnant women, lactating women, patients under 18 years of age and patients with epilepsy.

Precautions for children: The safety of children has not been established, so it is not suitable for use. Precautions for pregnancy and lactation: The safety of pregnant and lactating women has not been established, so pregnant and lactating women should not use it. Precautions for the elderly: This product is mainly eliminated by the kidneys. Some elderly patients have low renal function, which prolongs the half-life of the drug in the blood and maintains the blood concentration for a long time. Therefore, it should be used with caution and can be given in small doses (100 mg) at the beginning.

There are reports of occasional spasms when used simultaneously with similar compounds (enoxacin, norfloxacin) and non-steroidal anti-inflammatory analgesics such as fenbufen.

Store in a dark and airtight container (10-30℃).

0.1g

24 months

Shenyang Xinma Pharmaceutical Co., Ltd.

• Founded in:

  1998-11-09

• Address:

  No. 10 Xuelian Street, Sujiatun District, Shenyang

• Tax NO.:

  91210111711144908A

• Registered Funds:

  40 million yuan

• Website:

  Log in to view

• Email:

  Log in to view