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Galantamine Hydrobromide Dispersible Tablets

Function and Efficacy

This product is a selective, competitive and reversible acetylcholinesterase inhibitor. In addition, this product can also enhance the intrinsic effect of acetylcholine by binding to the allosteric site of nicotinic receptors. Through the above mechanism of action, the activity of the cholinergic system is enhanced, and the cognitive function of patients with Alzheimer's disease is improved.

Ingredients

Galantamine hydrobromide.

Name Description Content CAS NO. Manufacturer
Galantamine HydrobromideIngredients

This product is a selective, competitive and reversible acetylcholinesterase inhibitor. In addition, this product can also enhance the intrinsic effect of acetylcholine by binding to the allosteric site of nicotinic receptors. Through the above mechanism of action, the activity of the cholinergic system is enhanced, and the cognitive function of patients with Alzheimer's disease is improved.

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1953-04-4 16

Appearance

This product is white or off-white tablets.

Indication

No data yet

Usage and Dosage

Oral administration, it is recommended to take with breakfast and dinner. Starting dose: The recommended dose is 4 mg once, twice a day, for 4 weeks. Ensure adequate fluid intake during treatment. Maintenance dose: The initial maintenance dose is 8 mg once, twice a day. At this dose, the patient maintains it for at least 4 weeks. After a comprehensive evaluation of the patient's clinical efficacy and tolerability, the physician can increase the dose to the highest clinically recommended dose, 12 mg once, twice a day. Please refer to the relevant section of the instructions for precautions for use in special populations. Shiweibao has no withdrawal reaction.

Adverse Reactions

Nervous system: Fatigue, dizziness, headache, tremor, insomnia, and dreaminess are common. Hypertonia, paresthesia, aphasia, and hyperkinesia are rare. Gastrointestinal system: Abdominal distension, nausea, vomiting, abdominal pain, diarrhea, anorexia, weight loss, and indigestion are common. There are also reports of dysphagia and gastrointestinal bleeding. Cardiovascular system: Bradycardia and arrhythmia are seen. Hypotension is rare. Blood system: Anemia is seen, and thrombocytopenia is occasionally seen. Endocrine and metabolic system: Hyperglycemia is occasionally seen, and hypokalemia has been reported.

Precautions

This product is contraindicated for those who are allergic to any of the ingredients in this product. This product is a cholinesterase inhibitor and is contraindicated under anesthesia. It is contraindicated for patients with angina pectoris and bradycardia. It is contraindicated for patients with severe asthma or pulmonary dysfunction. It is contraindicated for patients with severe liver damage. It is contraindicated for patients with severe kidney damage. It is contraindicated for patients with mechanical intestinal obstruction, urinary tract obstruction or bladder surgery recovery period.

Special Population Medication

Precautions for children: There is no research information and data on the use of this product in children, so it is not recommended for children to use it. Precautions for pregnancy and lactation: There is no data on the use of this product in pregnant women, so pregnant women should weigh the pros and cons when using this product. It is not clear whether this product is excreted from breast milk, and there is no research data on breastfeeding women, so it is not recommended for breastfeeding women. Precautions for the elderly: It is not clear yet, please refer to the content under other items.

Drug Interactions

This product has the potential to weaken the therapeutic effect of anticholinergic drugs. It has a synergistic effect when used in combination with cholinergic drugs and other cholinesterase inhibitors. The bioavailability of this product can be increased when used in combination with imipenem and ketoconazole. The efficacy of this product can be reduced when used in combination with erythromycin. There are reports of atrioventricular conduction block when this product is used in combination with digoxin.

Storage

seal.

Packaging Specification

5mg

Validity Period

24 months

Manufacturer

Zhejiang YIXIN Pharmaceutical Co., Ltd.

  • Founded in:

    1993-01-20
  • Address:

    No. 5-1, Zhiyuan Road, Shanghua Street, Lanxi City, Zhejiang Province
  • Tax NO.:

    91330000147380685J
  • Registered Funds:

    40.1716 million yuan
  • Website:

  • Email:

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