Cinnarizine Capsules
Function and Efficacy
This product is a piperazine calcium channel antagonist, which can prevent pathological calcium influx in smooth muscle cells of vascular walls and relieve vascular spasm. It has the effect of dilating cerebral and peripheral blood vessels, improving cerebral circulation and coronary circulation, especially on cerebral blood vessels. This product can also inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the concentration of cAMP in cells, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4. The lethal dose for humans is 100-500 mg/kg, and the LD50 (oral administration for mice and rats) is greater than 1g/kg.
Ingredients
The main ingredients and chemical names of this product are: 1-diphenylmethyl-4-(3-phenyl-ethyl-propylene)-piperazine
Appearance
This product is capsule
Indication
It is used for the treatment of cerebral thrombosis, cerebral embolism, cerebral arteriosclerosis, cerebral hemorrhage recovery period, subarachnoid hemorrhage recovery period, sequelae of brain trauma, inner ear vertigo, coronary artery sclerosis and diseases caused by poor peripheral circulation. In recent years, relevant literature reports have shown that this product can be used for allergic skin diseases such as chronic urticaria and senile skin itching.
Usage and Dosage
Oral administration, 25-50 mg each time, 3 times a day.
Adverse Reactions
Common symptoms include drowsiness, fatigue, and weight gain in some patients (usually transient). Long-term use may occasionally cause depression and extrapyramidal reactions, such as involuntary movements, rigidity, and dry mouth, muscle pain, and rash in a few patients.
Precautions
Patients with a history of allergy to this drug or a history of depression are contraindicated using this drug.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
(1) When used in combination with alcohol, hypnotics or sedatives, the sedative effect is aggravated. (2) When used in combination with phenytoin sodium or carbamazepine, the blood concentration of cinnarizine can be reduced.
Storage
Shade, sealed and stored
Packaging Specification
25mg
Validity Period
24 months
Manufacturer
Sinopharm ZHIJUN(Shenzhen)PHARMACEUTICAL Co., Ltd.
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Founded in:
1985-12-11 -
Address:
No. 16, Lanqing 1st Road, Guanlan High-tech Park, Longhua New District, Shenzhen -
Tax NO.:
91440300192190290M -
Registered Funds:
200 million yuan -
Website:
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Email: