Nitrofurantoin enteric-coated tablets
Ingredients
Appearance
This product is an enteric solvent.
Usage and Dosage
Oral administration. 1. Adults take 50-100 mg once, 3-4 times a day. 2. Low dose for simple lower urinary tract infection: Children over 1 month old take 5-7 mg/kg per day, divided into 4 doses. The course of treatment is at least 1 week, or at least 3 days after the urine culture turns negative. For patients with recurrent urinary tract infection, take this product for prevention, 50-100 mg per day for adults, before bedtime, and 1 mg/kg per day for children.
Adverse Reactions
1. Gastrointestinal reactions such as nausea, vomiting, anorexia and diarrhea are common. 2. Allergic reactions such as rash, drug fever, granulocytopenia, hepatitis, etc. may also occur. Hemolytic anemia may occur in patients with glucose-6-phosphate dehydrogenase deficiency. 3. Adverse reactions of the nervous system such as headache, dizziness, drowsiness, myalgia, nystagmus, etc. may occasionally occur. Most of them are reversible. In severe cases, peripheral neuritis may occur. Patients with existing renal dysfunction or long-term use of this product are prone to it. 4. Nitrofurantoin may occasionally cause acute pneumonia symptoms such as fever, cough, chest pain, lung infiltration and eosinophilia, which may disappear quickly after discontinuation of the drug. Corticosteroids may alleviate symptoms in severe patients. Patients who take it for more than 6 months may occasionally develop interstitial pneumonia or pulmonary fibrosis. The drug should be stopped as soon as possible and corresponding treatment measures should be taken.
Precautions
It is contraindicated for newborns, full-term pregnant women, patients with impaired renal function, and patients allergic to nitrofurantoin-type drugs.
Special Population Medication
Precautions for children: It is contraindicated for newborns under 1 month old. Precautions for pregnancy and lactation: 1. Because nitrofurantoin can pass through the placental barrier and the fetal enzyme system is not fully developed, it is not suitable for pregnant women in the late pregnancy and is contraindicated for pregnant women at full term to avoid the possibility of hemolytic anemia in the fetus. 2. A small amount of nitrofurantoin can enter breast milk and induce hemolytic anemia in infants, especially those with glucose-6-phosphate dehydrogenase deficiency. Breastfeeding should be stopped when taking this product. Precautions for the elderly: Elderly patients should use it with caution and the dosage should be adjusted according to renal function.
Drug Interactions
1. When drugs that can cause hemolysis are used in combination with nitrofurantoin, the hemolytic reaction may be increased. 2. When used in combination with hepatotoxic drugs, the hepatotoxic reaction may be increased; when used in combination with neurotoxic drugs, the neurotoxicity may be increased. 3. Both probenecid and sulfinpyrazone can inhibit the renal tubular secretion of nitrofurantoin, resulting in an increase in the latter's blood concentration and (or) a prolonged serum half-life, while the urine concentration is reduced and the efficacy is also weakened. The dosage of probenecid and the like should be adjusted.
Storage
seal.
Packaging Specification
50mg*100s
Validity Period
24 months
Manufacturer
Jilin Fultai Pharmaceutical Co., Ltd.
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Founded in:
2015-12-04 -
Address:
No. 151, Jikang Road, Nankang Street, Longshan District, Liaoyuan City, Jilin Province -
Tax NO.:
91220400MA0Y3GD27T -
Registered Funds:
15 million yuan -
Email: