Bone melon extract injection

Pharmacological experiments show that this product contains a variety of active peptides for bone metabolism, which can regulate bone metabolism, stimulate osteoblast proliferation, promote new bone formation, regulate calcium and phosphorus metabolism, increase bone calcium deposition, prevent and treat osteoporosis, and have anti-inflammatory and analgesic effects. 1. The role of polypeptide bone metabolic factors: Polypeptide bone metabolic factors can effectively promote the synthesis of bone-derived growth factors that affect bone formation and absorption in the body, including bone morphogenetic proteins (BMPs), beta;-transforming growth factor (TGF-beta;), fibroblast growth factor (FGF), etc., thus having a variety of biological activities. Its main pharmacological effects are: promoting cell mitosis, differentiation, chemotaxis and osteolytic activity. Among them, BMPs is a group of acidic low molecular weight glycoproteins. As a highly effective bone inducing substance, BMPs are the initial signal molecules for the differentiation of mesenchymal cells into bone cells. They can induce mesenchymal cells swimming around blood vessels to transform into irreversible bone cells, namely chondrocytes and osteoblasts, thereby promoting callus formation, inducing new bone formation, and promoting fracture repair; in addition, BMPs can also regulate changes in extracellular matrix components, and through the coordinated effect with TGF-beta and FGF, better induce new bone formation and make bone tissue more mature. TGF-beta is a group of protein polypeptides with multiple functions. It has a dual regulatory effect on osteoblasts and chondrocytes, promoting or reducing differentiation. It works together with multiple factors such as extracellular matrix and other differentiation-regulating growth factors to regulate cell differentiation. TGF-beta can promote the synthesis of extracellular matrix, directly stimulate the synthesis of extracellular matrix of fibroblasts, and significantly inhibit the degradation of newly synthesized matrix. For osteoblasts, TGF-beta can promote the synthesis of type I collagen, osteonectin and osteopontin. At the same time, the effect of TGF-beta on lymphocytes and macrophages shows that it can alleviate the destructiveness of inflammatory reactions and assist certain cytokines derived from macrophages in tissue repair. FGF is a group of heparin-binding polypeptides that can stimulate cell migration, proliferation and differentiation, increase the number of cells that synthesize collagen, promote the synthesis of bone collagen and non-collagenous proteins, and increase the synthesis of osteocalcin. 2. The role of melon seed extract: Melon seed extract is extracted from the mature and dried seeds of the Cucurbitaceae plant Cucumis melo (Cucumis melo L.) through a special process. It can reduce the permeability of local capillaries in the fracture, reduce inflammatory exudation, and promote the recovery of local blood supply disorders; at the same time, it can also reduce the viscosity of whole blood and the degree of cell aggregation, improve the blood circulation of the local bone sclerosis, and provide a good blood supply environment for bone cells; in addition, it can inhibit the release of prostaglandins to achieve analgesic effects; in promoting early fracture healing, melon seed extract has a synergistic effect with supplementary polypeptide bone metabolic factors to promote the synthesis of bone-derived growth factors. 3. The role of other ingredients: This product is rich in a variety of free chlorogenic acids, which provide raw materials for bone cells to synthesize BMPs, TGF-beta;, FGF and other bone-derived biological factors, and promote the synthesis of bone-derived biological factors. Organic calcium and phosphorus ions can participate in calcium and phosphorus metabolism and maintain bone capacity.

Polypeptide bone metabolic factors, melon seed extract, various free amino acids, as well as organic calcium, inorganic calcium, phosphorus ions, inorganic salts and trace elements.

Used for rheumatism, rheumatoid arthritis, osteoarthritis, low back and leg pain, and fracture trauma repair.

1. Intramuscular injection: 2-5 ml at a time, twice a day. 2. Intravenous drip: 10-20 ml at a time, added to 250 ml 0.9% sodium chloride injection or 5% glucose injection, once a day, 20-30 days as a course of treatment; or follow the doctor's advice.

No adverse reactions have been reported.

1. It is contraindicated for those who are allergic to this product. 2. It is contraindicated for those with severe renal insufficiency.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Not yet clear.

Keep tightly closed.

5ml:25mg

24 months

Harbin Songhe Pharmaceutical Co., Ltd.

• Founded in:

  2002-04-28

• Address:

  Harbin Niujia Industrial Park

• Tax NO.:

  912301841270421874

• Registered Funds:

  27 million yuan

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