Irbesartan Tablets

This product is an angiotensin II (Ang II) receptor inhibitor, which can inhibit the conversion of Ang I to Ang II, and can specifically antagonize angiotensin converting enzyme 1 receptor (AT1). Its antagonism to AT1 is greater than AT28500 times. It selectively blocks the binding of Ang II to AT1 receptor, inhibits vasoconstriction and the release of aldosterone, and produces a hypotensive effect. This product does not inhibit angiotensin converting enzyme (ACE), renin, other hormone receptors, nor does it inhibit ion channels related to blood pressure regulation and sodium balance.

The main ingredient of this product is irbesartan.

This product is white to off-white tablets.

Used to treat hypertension.

Oral: The recommended starting dose is 0.15g, once a day. It can be increased to 0.3g, once a day, depending on the condition. It can be used alone or in combination with other antihypertensive drugs. For severe hypertension and when the blood pressure is still not reduced satisfactorily after the increase in drug dosage, a small dose of diuretics (such as thiazides) or other antihypertensive drugs can be added.

Common adverse reactions are: headache, dizziness, palpitations, etc., and occasional cough, which are generally mild and transient, and most patients can tolerate it by continuing to take the medicine. Urticaria and angioedema are rare. Literature reports that the incidence of adverse reactions of this product is greater than 1% including: indigestion, heartburn, diarrhea, skeletal muscle pain, fatigue and upper respiratory tract infection, but there is no significant difference compared with the blank control group. The incidence of adverse reactions greater than 1% but lower than the control group includes abdominal pain, anxiety, nervousness, chest pain, pharyngitis, nausea and vomiting, rash, tachycardia, etc. The incidence of hypotension and orthostatic hypotension is about 0.4%

It is contraindicated for those who are allergic to this product.

1. When this product is used in combination with diuretics, attention should be paid to insufficient blood volume or hypotension caused by low sodium. When used in combination with potassium-sparing diuretics (such as triamterene, etc.), elevated blood potassium should be avoided. 2. There is no obvious interaction between this product and warfarin. 3. When used in combination with digitalis drugs such as digoxin, blockers such as atenolol, calcium antagonists such as nifedipine, etc., it does not affect the pharmacokinetics of each other.

Sealed storage

75mg*12 tablets/box

36 months

Anhui Globe Pharmaceutical Co., Ltd.

• Founded in:

  2000-11-13

• Address:

  No. 3809 Huangshan Avenue, Bengbu City

• Tax NO.:

  91340300723348633W

• Registered Funds:

  98.5 million yuan

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