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Acyclovir eye drops

Function and Efficacy

Acyclovir (AZV) is effective against herpes simplex virus (HSV) type I and II, and secondarily against varicella-zoster virus (AZV), but has a weaker effect on Epstein-Barr virus and cytomegalovirus. Acyclovir is effective against herpes simplex virus type I and II and varicella-zoster virus because AZV can be phosphorylated by virus-encoded thymidine kinase (TK) into acyclovir monophosphate, which is then catalyzed by cellular enzymes to form acyclovir diphosphate and triphosphate. Acyclovir triphosphate is a strong inhibitor of herpes simplex virus DNA polymerase. It binds to the enzyme as a substrate of viral DNA polymerase and is incorporated into viral DNA, thereby terminating the synthesis of viral DNA.

Ingredients

Chemical name of this product: 9-(2-hydroxyethoxymethyl)guanine. Molecular formula: C8H10N5NaO3 Molecular weight: 247.2

Name Description Content CAS NO. Manufacturer
AcyclovirIngredients

It is effective against herpes simplex virus (HSV) type I and II, and secondarily against varicella-zoster virus, but less effective against Epstein-Barr virus and cytomegalovirus. Acyclovir is effective against herpes simplex virus type I and II and varicella-zoster virus because AZV can be phosphorylated by virus-encoded thymidine kinase (TK) into acyclovir monophosphate, which is then catalyzed by cellular enzymes to form acyclovir diphosphate and triphosphate. Acyclovir triphosphate is a strong inhibitor of herpes simplex virus DNA polymerase. It binds to the enzyme as a substrate of viral DNA polymerase and is incorporated into viral DNA, thereby terminating the synthesis of viral DNA.

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Appearance

This product is a colorless clear liquid.

Indication

Antiviral drug. Used for herpes simplex keratitis.

Usage and Dosage

Place drops into eyelids every 2 hours.

Adverse Reactions

Eye drops may cause mild pain and burning sensation, but are well tolerated by patients.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Not yet clear.

Storage

Sealed and light-proof.

Packaging Specification

8ml:8mg

Validity Period

36 months

Manufacturer

Shanghai Xiao Fang Pharmaceutical Co.,Ltd.

  • Founded in:

    1993-08-12
  • Address:

    No. 777, Hongzhu Road, Fengxian District, Shanghai
  • Tax NO.:

    91310000607233687D
  • Registered Funds:

    160 million yuan
  • Website:

  • Email:

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