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Econazole nitrate cream

Function and Efficacy

This product is an azole antifungal drug and a dechlorinated derivative of miconazole. This product has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. This product has poor effects on Aspergillus, Sporothrix Schenckii, some dark-colored spores, Mucor, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.

Ingredients

Econazole nitrate

Name Description Content CAS NO. Manufacturer
Econazole nitrateIngredients

This product is an azole antifungal drug. It has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc. It also has antibacterial activity against Trichophyton, etc. It inhibits the biosynthesis of ergosterol in the fungal cell membrane by interfering with the activity of cytochrome P-450, damages the fungal cell membrane and changes its permeability, resulting in leakage of intracellular substances. It can inhibit the biosynthesis of triglycerides and phospholipids in fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.

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68797-31-9 18

Appearance

This product is a milky white ointment with an emulsion base.

Indication

This product is suitable for the treatment of skin candidiasis; it can also be used to treat tinea corporis, tinea cruris, tinea pedis, tinea versicolor, etc.

Usage and Dosage

Topical application: For skin candidiasis and various tinea, apply once in the morning and evening each day, for 2 to 4 weeks; for tinea versicolor, apply once a day.

Adverse Reactions

Some patients experience local irritation and occasionally allergic reactions, manifested as burning sensation, itching, tingling, congestion, etc.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions during pregnancy and lactation: Not yet clear.

Drug Interactions

Not yet clear.

Storage

Keep tightly closed in a cool place.

Packaging Specification

1%

Validity Period

24 months

Manufacturer

Fujian Sanming Tiantai Pharmaceutical Co., Ltd.

  • Founded in:

    2004-04-23
  • Address:

    No. 138, Xincheng East Road, Fenggang Street, Sha County, Fujian Province
  • Tax NO.:

    91350427761761779R
  • Registered Funds:

    35 million yuan
  • Email:

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