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Cefaclor Capsules

Function and Efficacy

Antibacterial drug. It is relatively stable against the β-lactamase produced by Staphylococcus aureus, so it has a strong antibacterial effect against Gram-positive bacteria; it is unstable against the β-lactamase produced by Gram-negative bacteria, so it has a weaker effect against Gram-negative bacteria, and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

Ingredients

Main ingredient: Cefaclor

Name Description Content CAS NO. Manufacturer
CefaclorIngredients

Antibacterial drug. It is relatively stable against the β-lactamase produced by Staphylococcus aureus, so it has a strong antibacterial effect against Gram-positive bacteria; it is unstable against the β-lactamase produced by Gram-negative bacteria, so it has a weaker effect against Gram-negative bacteria, and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

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53994-73-3 29

Appearance

Capsules, the contents are white to light yellow powder.

Indication

It is mainly used for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

Oral: The usual adult dose is 0.25g once, 3 times a day. The dose can be doubled for patients with severe infection, but the total daily amount should not exceed 4.0g. Or follow the doctor's advice.

Adverse Reactions

1 Gastrointestinal: diarrhea, stomach discomfort, nausea, vomiting, etc. 2 Allergic reactions: urticaria, rash, eosinophilia, vulvar itching. 3 Others: mild increase in aminotransferase, plasma urea nitrogen (BUN) and creatinine (Cr), proteinuria, casts, etc.

Precautions

1 This product has cross-allergic reactions with penicillins or cephamycins, so it should be used with caution in patients who are allergic to penicillins, penicillin derivatives, penicillamine and cephamycins. 2 Use with caution in patients with renal impairment and liver damage. 3 Use with caution in patients with a history of gastrointestinal diseases, especially ulcerative colitis, regional enteritis or antibiotic-related colitis. 4 Long-term use of this product may cause dysbacteriosis and induce secondary infection. 5 Interference with laboratory test indicators: The antiglobulin (Coombs) test may be positive; the copper sulfate urine glucose test may be false positive, but the glucose enzyme test method is not affected; serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and blood urea nitrogen may be elevated; the Jaffe reaction is used for serum and urine

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other antineoplastic drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of lactamase. 3. Oral administration of probenecid can delay the excretion of this product.

Storage

Keep in a dark, sealed and cool dry place. Valid for 2 years.

Packaging Specification

0.25 g (calculated as C15H14ClN3O4S)

Validity Period

24 months

Manufacturer

Haikou Pharmaceutical Factory Co., Ltd.

  • Founded in:

    1990-03-09
  • Address:

    No. 192, Nanhai Avenue, Xiuying District, Haikou City, Hainan Province
  • Tax NO.:

    91460100984090386D
  • Registered Funds:

    562.352031 yuan
  • Email:

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