Cefaclor Granules

This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls.

The main ingredient of this product is cefaclor. Its chemical name is: (6R, 7R)-7-[(R)-2-amino-2-phenylacetylamino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate.

This product is a suspension granule with aromatic odor and sweet taste.

This product is mainly suitable for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.

This product is suitable for oral administration on an empty stomach. Add this product to an appropriate amount (20-30ml) of hot water and take it after shaking completely. The usual dosage for adults is 0.25g at a time (0.1g: 2.5 bags; 0.125g: 2 bags; 0.25g: 1 bag), 3 times a day. In case of severe infection, the dosage can be doubled, but the total daily dosage should not exceed 4g (0.1g: 40 bags; 0.125g: 32 bags; 0.25g: 16 bags), or follow the doctor's advice. Children are generally given 20mg/kg per day according to body weight, divided into 3 times. In severe infection, it can be increased to 40mg/kg, but the total daily dosage should not exceed 1g (0.1g: 10 bags; 0.125g: 8 bags; 0.25g: 4 bags).

1. Common gastrointestinal reactions: soft stools, diarrhea, stomach discomfort, loss of appetite, nausea, vomiting, heating, etc. 2. Serum sickness-like reactions are more common than other antibiotics, especially in children, with typical symptoms including skin reactions and joint pain. 3. Allergic reactions: rash, urticaria, eosinophilia, vulvar itching, etc. 4. Others: mild increase in serum aminotransferase, urea nitrogen and creatinine, proteinuria, cystic urine, etc.

Patients who are allergic to cefaclor and other cephalosporins are contraindicated.

Precautions for children: Not clear yet. Precautions for pregnancy and lactation: 1. Use with caution in pregnant women. 2. This product can be excreted through breast milk, so lactating women should use it with caution or stop breastfeeding. Precautions for the elderly: Elderly patients should adjust the dosage or medication according to their renal function under the guidance of a physician.

1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other anti-tumor drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of β-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.

Keep away from light, seal tightly, and store in a cool, dark, and dry place. Validity period: 24 months

0.125g

24 months

Haikou Pharmaceutical Factory Co., Ltd.

• Founded in:

  1990-03-09

• Address:

  No. 192, Nanhai Avenue, Xiuying District, Haikou City, Hainan Province

• Tax NO.:

  91460100984090386D

• Registered Funds:

  562.352031 yuan

• Email:

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