Lincomycin Hydrochloride Ear Drops
Function and Efficacy
1. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus, Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against anaerobic bacteria, such as Bacteroides including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, Clostridium perfringens, etc. Most of them are highly sensitive to this product. Gram-negative aerobic bacteria including Haemophilus influenzae, Neisseria and Mycoplasma are resistant to this product. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins and tetracyclines, but it has partial cross-resistance with macrolides and complete cross-resistance with clindamycin. 2. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the extension of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.
Ingredients
The lincomycin hydrochloride contained in this product, calculated as lincomycin (C18H34N2O6S), should be 90.0% to 110.0% of the labeled amount.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Lincomycin hydrochlorideIngredients |
It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus, Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc., and also has good antibacterial activity against anaerobic bacteria. The mechanism of action is to bind to the 50S subunit of bacterial ribosomes, prevent the extension of peptide chains, and thus inhibit protein synthesis in bacterial cells. At high concentrations, it also has a bactericidal effect on certain bacteria. More |
859-18-7 | 30 |
Appearance
This product is a colorless clear liquid.
Indication
It is mainly used for patients with acute and chronic suppurative otitis media with tympanic membrane perforation caused by Gram-positive bacteria and anaerobic bacteria.
Usage and Dosage
When dripping the medicine, the person who drips the medicine should pull the patient's auricle backward and downward to straighten the ear canal. The dropper of the ear dropper should not touch the external ear canal to avoid contamination. 3 to 5 drops of the medicine should be dripped each time, and then the tragus (the protruding part in front of the ear) should be gently pressed several times to allow the medicine to enter the middle ear. Finally, a sterilized cotton ball can be used to plug the opening of the external ear canal. Generally, the medicine should be dripped 3 times a day.
Adverse Reactions
Occasionally, there may be allergic reactions such as rash and itching; neutropenia, thrombocytopenia, candida infection, etc. There are also side effects such as tinnitus and dizziness.
Precautions
1. It is contraindicated for those who are allergic to lincomycin. 2. It is contraindicated for infants under 1 month old.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
Keep tightly closed in a cool, dark and dry place.
Packaging Specification
6ml: 180,000 units (calculated as C18H34N2O6S)
Validity Period
24 months