Tegafur Capsules
Function and Efficacy
This product is a derivative of fluorouracil. It is activated by the liver in the body and gradually converted into fluorouracil to play an anti-tumor role. It can interfere with and block the synthesis of DNA, RNA and protein, and mainly acts on the S phase. It is a cell cycle-specific drug of anti-pyrimidine. Its mechanism of action, efficacy and anti-tumor spectrum are similar to those of fluorouracil, but it has a long-lasting effect, good absorption and low toxicity. The chemotherapy index is twice that of fluorouracil, and the toxicity is only 1/4 to 1/7 of that of fluorouracil. No serious bone marrow suppression was observed in the chronic toxicity experiment, and the effect on immunity was relatively mild.
Ingredients
The chemical name of this product is: 1-(tetrahydro-2-furanyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione. Its structural formula is: Molecular formula: C8H9FN2O3 Molecular weight: 200.17
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| TegafurIngredients |
This product is a derivative of fluorouracil. It is activated by the liver in the body and gradually converted into fluorouracil to play an anti-tumor role. It can interfere with and block the synthesis of DNA, RNA and protein, and mainly acts on the S phase. It is a cell cycle-specific drug of anti-pyrimidine. Its mechanism of action, efficacy and anti-tumor spectrum are similar to those of fluorouracil, but it has a long-lasting effect, good absorption and low toxicity. The chemotherapy index is twice that of fluorouracil, and the toxicity is only 1/4 to 1/7 of that of fluorouracil. No serious bone marrow suppression was observed in the chronic toxicity experiment, and the effect on immunity was relatively mild. More |
17902-23-7 | 10 |
Appearance
This product is a capsule containing white powder.
Indication
It is mainly used to treat digestive tract tumors, and has certain effects on gastric cancer, colon cancer, and rectal cancer. It can also be used to treat breast cancer, bronchial lung cancer, liver cancer, etc. It can also be used for bladder cancer, prostate cancer, kidney cancer, etc.
Usage and Dosage
For adults, take orally, 800-1200 mg per day, divided into 3-4 doses, with a total amount of 30-50 g per course of treatment.
Adverse Reactions
Mild bone marrow suppression is manifested by leukopenia and thrombocytopenia. Mild gastrointestinal reactions are mainly loss of appetite and nausea. Some patients may experience vomiting, diarrhea and abdominal pain, which may disappear after stopping the drug. Other reactions include fatigue, chills, fever, headache, dizziness, movement disorders, skin itching, pigmentation, mucositis and vascular pain at the injection site.
Precautions
It is contraindicated for those who are allergic to this product.
Drug Interactions
Tegafur is alkaline and contains carbonate. Avoid using it with drugs containing calcium or magnesium ions or with strong acidity.
Storage
Sealed storage
Packaging Specification
0.2g
Manufacturer
Chengdu Tongde Pharmaceutical Co., Ltd.
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Founded in:
1987-08-28 -
Address:
Section B, Liutai Avenue, Chengdu Cross-Strait Science and Technology Industrial Development Park -
Tax NO.:
91510115201946724T -
Registered Funds:
70 million yuan -
Website:
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Email: