Nifedipine

1. This product can simultaneously relax the coronary arteries in the normal blood supply area and the ischemic area, antagonize spontaneous or ergonovine-induced coronary artery spasm, increase the delivery of myocardial oxygen to patients with coronary artery spasm, and relieve and prevent coronary artery spasm. 2. This product can inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption. 3. This product can relax peripheral resistance vessels, reduce peripheral resistance, and can reduce systolic and diastolic blood pressure, reducing cardiac afterload. 4. This product can delay the sinus node function and atrioventricular conduction of the isolated heart; electrophysiological studies of whole animals and humans have not found that this product has the effect of delaying atrioventricular conduction, prolonging the recovery time of the sinus node, and slowing down the sinus node rate.

Nifedipine

Clinically applicable to the prevention and treatment of angina pectoris caused by coronary heart disease, especially variant angina pectoris and angina pectoris caused by coronary artery spasm. Applicable to various types of hypertension, and also has good efficacy on refractory and severe hypertension. Raynaud's syndrome. Because it can reduce afterload, it also has good efficacy on refractory congestive heart failure and is suitable for long-term use. In addition, it is also suitable for patients with angina pectoris suffering from obstructive respiratory diseases, and its efficacy is better than beta-receptor blockers.

Headache, flushing of the face and skin, hot flashes, tachycardia, palpitations, dizziness, fatigue. Hypotension. Swelling of the calves and ankles. Gastrointestinal disturbances such as nausea and diarrhea in extreme cases. Skin reactions such as itching, urticaria, and rashes. Long-term use in elderly male patients may cause gynecomastia. Long-term use may also cause gingival hyperplasia. May impair the ability to drive and operate machinery. Overdose may cause bradycardia and hypotension. Some cases may cause numbness at the root of the tongue, dry mouth, sweating, headache, nausea, and loss of appetite.

Patients with hypotension, allergy to dihydropyridine drugs, cardiovascular shock, acute stage of myocardial infarction (within 8 days).

Combination with other antihypertensive drugs can enhance the antihypertensive effect. Severe hypotension may occur when used simultaneously with B-receptor blockers. When used simultaneously with digoxin, digoxin clearance may be reduced. When taken simultaneously with quinidine, quinidine concentration decreases. Cimetidine or ranitidine may slightly increase the concentration of this drug.

Shaanxi XIYUE Pharmaceutical Co., Ltd.

• Founded in:

  1992-11-08

• Address:

  Huashan Town, Huayin City, Weinan City, Shaanxi Province

• Tax NO.:

  916105006231023535

• Registered Funds:

  50 million yuan

• Website:

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