Clodronate Disodium Capsules

This product is a bone metabolism regulator that can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts.

Clodronate disodium

Capsules, the contents are white crystalline powder.

1. Hypercalcemia complicated by malignant tumors. 2. Bone pain caused by osteolytic cancer metastasis. 3. Can avoid or delay osteolytic bone metastasis of malignant tumors. 4. Various types of osteoporosis.

Oral administration: Patients with malignant tumors: 2.4g per day, which can be taken in 2-3 times. For patients with normal serum calcium levels, it can be reduced to 1.6g per day. If accompanied by hypercalcemia, it can be increased to 3.2g per day. It must be taken on an empty stomach, preferably 1 hour before meals. Early or all types of osteoporosis without bone pain: 0.4g per day, 3 months as a course of treatment, and the course can be repeated if necessary. Severe or all types of osteoporosis with bone pain: 1.6g per day, taken in two times, or as directed by a doctor.

1. At the beginning of treatment, abdominal pain, bloating and diarrhea may occur, and in rare cases, dizziness and fatigue may occur, but they often disappear as treatment continues. 2. Sometimes, adverse reactions such as increased serum lactate dehydrogenase and other liver enzyme levels, leukopenia and abnormal renal function may occur.

1. Patients who are allergic to this product are prohibited from using this product. 2. Patients with severe renal impairment and osteomalacia are prohibited from using this product.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Not yet clear

Sealed, store in a dry place.

400 mg

60 months