Pefloxacin Mesylate Injection
Function and Efficacy
Pefloxacin mesylate is a quinolone antibacterial drug, and its mechanism of action is to inhibit bacterial DNA helicase. It has a broad-spectrum antibacterial effect, and has strong antibacterial activity against Enterobacter bacteria such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella typhi, etc., as well as influenza bacillus, Neisseria, etc. It also has a certain antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa. It has only a mild effect on pneumococci, various groups of streptococci and enterococci.
Ingredients
The main ingredient of this product is pefloxacin mesylate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Pefloxacin mesylateIngredients |
Quinolone antibiotics inhibit bacterial DNA gyrase and have antibacterial effects on Enterobacter, H. influenzae, Neisseria, Staphylococcus aureus and Pseudomonas aeruginosa, but only have mild effects on pneumococci, streptococci and enterococci. More |
70458-95-6 | 4 |
Appearance
This product is a colorless to slightly yellow or slightly yellowish green clear liquid.
Indication
Various infections caused by pefloxacin-sensitive bacteria: urinary tract infections; respiratory tract infections; ear, nose and throat infections; gynecological and reproductive system infections; abdominal and liver and gallbladder system infections; bone and joint infections; skin infections; sepsis and endocarditis; meningitis.
Usage and Dosage
Intravenous drip: Common adult dosage, 0.4g at a time, add to 250ml of 5% glucose solution and slowly drip intravenously, once every 12 hours. Patients with jaundice should take the medicine once a day; patients with ascites should take the medicine once every 36 hours; patients with jaundice and ascites should take the medicine once every 48 hours. Or follow the doctor's advice.
Adverse Reactions
A small number of patients may experience: 1. Gastrointestinal reactions, such as nausea, vomiting, loss of appetite, diarrhea, etc. 2. Photosensitivity reactions, nervous system reactions, such as dizziness, vertigo, headache, tremor, insomnia, etc. 3. Rash, increased serum aspartate aminotransferase and alanine aminotransferase, decreased white blood cells, etc. 4. Occasionally, local irritation symptoms after injection. The above reactions are all mild to moderate reactions and will disappear after stopping the drug.
Precautions
It is contraindicated for patients who are allergic to this product or other quinolones or those with insufficient 6-phosphate glucose dehydrogenase.
Special Population Medication
Precautions for children: The safety of this product in infants and adolescents under 18 years of age has not been determined. However, this product can cause joint lesions when used in several young animals. Therefore, it is contraindicated in patients under 18 years of age. Precautions for pregnancy and lactation: Animal experiments have not confirmed that quinolones are teratogenic, but studies on the use of drugs in pregnant women have not yet reached a clear conclusion. Since this drug can cause joint lesions in underage animals, it is contraindicated in pregnant women, and lactating women should suspend breastfeeding when using this product.
Drug Interactions
1 Avoid taking theophylline, magnesium or aluminum hydroxide antacids at the same time. 2 Do not use sodium chloride solution or other solutions containing chloride ions as diluent.
Storage
Keep away from light, tightly closed, in a cool place.
Packaging Specification
5ml:0.4g (calculated according to C17H20FN3O3)
Validity Period
24 months
Manufacturer
Changchun Norman Bethune Pharmaceutical Co., Ltd.
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Founded in:
1985-12-06 -
Address:
No. 358, Chuangxin Road, High-tech Industrial Development Zone, Changchun City, Jilin Province -
Tax NO.:
91220101123997525C -
Registered Funds:
64.4778 million yuan -
Website:
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Email: