Midecamycin Capsules

This product is a macrolide antibiotic produced by Streptomyces mycarofaciens. It works by acting on the 50S subunit of bacterial ribosomes, hindering the synthesis of bacterial proteins, and is a growth-stage antibacterial drug. Its antibacterial properties are similar to those of erythromycin, and it shows strong antibacterial effects on Gram-positive bacteria and mycoplasmas, and also has antibacterial effects on some Gram-negative bacteria such as Neisseria meningitidis and Neisseria gonorrhoeae.

The main ingredient of this product is midecamycin. Its chemical name is [4R-(4R*,5S*,6S*,7R*,9R*,10R*,11E,13E,16R*)]-6-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-carbon-methyl-a-L-ribose-hexopyranosyl)-3-(dimethylamino)-b-D-pyranoglucopyranosyl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxohexaane-11,13-diene-7-acetaldehyde 3,4-b-dipropionate.

This product is in the form of capsules.

It is mainly suitable for respiratory tract infections and skin, soft tissue and bile tract infections caused by Staphylococcus aureus, hemolytic Streptococcus, Pneumococcus, etc., and can also be used for Mycoplasma pneumonia.

Oral administration: 0.8-1.2g per day for adults, 30-40mg/kg per day for children according to body weight. Take in 3-4 doses.

1. Hepatotoxicity: At normal doses, the hepatotoxicity of this product is relatively small, mainly manifested as cholestasis and temporary elevation of serum aminotransferase, which can generally be restored after discontinuation of the drug. 2. Allergic reactions: Mainly manifested as drug fever, drug rash and urticaria. 3. Occasionally, gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort, and loss of appetite may occur.

Patients who are allergic to this product and macrolide drugs are contraindicated.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.

Oral administration: 0.8-1.2g per day for adults, 30-40mg/kg per day for children according to body weight. Take in 3-4 doses.

0.1g

24 months

Hainan Pharmaceutical FACTORY Co., Ltd.

• Founded in:

  2001-07-09

• Address:

  Hebei West Road, Wuzhishan City, Hainan Province

• Tax NO.:

  91469001730040768G

• Registered Funds:

  12.8 million yuan

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