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Domperidone Tablets

Function and Efficacy

This product is a peripheral dopamine receptor blocker that acts directly on the gastrointestinal wall, can increase the tension of the lower esophageal sphincter, prevent gastroesophageal reflux, enhance gastric motility, promote gastric emptying, coordinate gastric and duodenal motility, inhibit nausea and vomiting, and effectively prevent bile reflux without affecting gastric juice secretion. This product is not easy to pass through the blood-cerebrospinal fluid barrier and has an inhibitory effect on dopamine receptors in the brain. Therefore, there are no extrapyramidal and other neurological and psychiatric adverse reactions.

Ingredients

The main ingredient of this product is domperidone, and its chemical name is 5-chloro-1[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidinyl]-2-benzimidazolinone. Molecular formula: C22H24ClN5O2

Name Description Content CAS NO. Manufacturer
DomperidoneIngredients

Peripheral dopamine receptor blockers act directly on the gastrointestinal wall, increase the tension of the lower esophageal sphincter, prevent gastroesophageal reflux, enhance gastric motility, promote gastric emptying, coordinate gastric and duodenal movements, inhibit nausea and vomiting, and effectively prevent bile reflux without affecting gastric juice secretion. It is not easy to pass through the blood-cerebrospinal fluid barrier, and has an inhibitory effect on dopamine receptors in the brain, without extrapyramidal and other neurological and psychiatric adverse reactions.

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57808-66-9 19

Appearance

White flakes

Indication

1. Relieve indigestion symptoms caused by delayed gastric emptying, gastrointestinal reflux, and esophagitis, such as upper abdominal fullness, bloating, upper abdominal pain, belching, flatulence, and burning sensation in the mouth with or without gastric contents. 2. Treat nausea and vomiting caused by functional, organic, infectious, dietary, radiotherapy or chemotherapy.

Usage and Dosage

Oral administration: 1. Adults: 3 to 4 times a day, 10 mg each time, the dose can be doubled if necessary or follow the doctor's advice. 2. Children: 3 to 4 times a day, 0.3 mg per kilogram of body weight each time, this product should be taken 15 to 30 minutes before meals.

Adverse Reactions

1 Mild abdominal cramps, dry mouth, rash, headache, diarrhea, nervousness, fatigue, drowsiness, dizziness, etc. may occur occasionally; 2 Sometimes serum prolactin levels may increase, galactorrhea, and feminization of male breasts may occur, but they will return to normal after stopping the drug.

Precautions

It is contraindicated for use in diseases such as pheochromocytoma, breast cancer, mechanical intestinal obstruction, and gastrointestinal bleeding.

Special Population Medication

Precautions for children: Due to the incomplete development of the blood-cerebrospinal fluid barrier in children under 1 year old, the possibility of central nervous system side effects in infants under 1 year old cannot be ruled out. Precautions for pregnancy and lactation: Use with caution in pregnant women. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Anticholinergic drugs such as acetaminophen, propantheline bromide, scopolamine, belladonna tablets, etc. will weaken the effect of this product and should not be taken together; 2. When this product is used together with acetaminophen, ampicillin, levodopa, tetracycline, etc., the absorption rate of these drugs will increase; 3. When this product is used together with digoxin, the absorption of the latter will be reduced; 4. If you are taking other medicines, please consult a doctor or pharmacist before using this product.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

10mg

Validity Period

24 months

Manufacturer

Shanxi Baotai Pharmaceutical Co., Ltd.

  • Founded in:

    1999-08-25
  • Address:

    Jianye Street, Huitong Industrial Park, Jinzhong Development Zone, Shanxi Demonstration Zone, Jinzhong City, Shanxi Province
  • Tax NO.:

    911407007159633615
  • Registered Funds:

    23.3 million yuan
  • Website:

  • Email:

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