Diclofenac Potassium Capsules

1 Pharmacology This product belongs to the azole antifungal drug. It has a wide antifungal spectrum. Oral and intravenous injection of this product is effective against fungal infections in humans and various animals, such as Candida infections (including systemic candidiasis in humans and animals with normal or impaired immunity), Cryptococcus neoformans infections (including intracranial infections), Malassezia furfur, Microsporum, Trichophyton, Epidermophyton, Blastomyces dermatitidis, Coccidioides immitis (including intracranial infections) and Histoplasma capsulatum, F. fischeri, and Cladosporium carinii. The in vitro antibacterial activity of this product is significantly lower than that of ketoconazole, but the in vivo antibacterial activity of this product is significantly higher than that of in vitro effects. The mechanism of action of this product is mainly to highly selectively interfere with the activity of fungal cytochrome P-450, thereby inhibiting the biosynthesis of ergosterol on the fungal cell membrane. 2 Toxicology This product is highly selective for the cytochrome P-450 enzyme that fungi depend on. Taking 0.5g of this product per day for 28 consecutive days has been shown to have no effect on the plasma testosterone concentration in men or the steroid hormone concentration in women of childbearing age.

Fluconazole. The chemical name of this drug is 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-2-propanol, the molecular formula is C13H12F2N6O, and the molecular weight is 306.27.

This medicine is a colorless, clear liquid.

1. Candidiasis: used to treat oropharyngeal and esophageal candidiasis; disseminated candidiasis, including peritonitis, pneumonia, urinary tract infection, etc.; candidal vulvovaginitis. It can also be used to prevent candidal infections in bone marrow transplant patients receiving cytotoxic drugs or radiotherapy. 2. Cryptococcosis: used to treat new cryptococcosis other than meninges; when treating cryptococcal meningitis, this product can be used as a maintenance therapy after initial treatment with amphotericin B combined with flucytosine. 3. Coccidioidomycosis. 4. This product can also replace itraconazole for the treatment of blastomycosis and histoplasmosis.

For external use, spray on affected area.

...

Patients with a history of allergy to this product or other azole drugs are contraindicated.

Precautions for children: Not recommended for use under 14 years of age or under doctor's advice. Precautions for pregnancy and lactation: Use with caution in pregnant women, especially in the first and last three months of pregnancy. This product enters breast milk in very small amounts. Precautions for the elderly: Use with caution in elderly patients, and if used, close observation should be made during medication.

1 When this product is used in combination with isoniazid or rifampicin, the concentration of this product can be reduced. 2 When this product is used in combination with sulfonylurea hypoglycemic drugs such as tolbutamide, chlorbutamide and glipizide, the blood concentration of these drugs can be increased, which may lead to hypoglycemia. Therefore, blood sugar needs to be monitored and the dose of sulfonylurea hypoglycemic drugs needs to be reduced. 3 When this product is used in combination with cyclosporine, the blood concentration of cyclosporine can be increased, which increases the risk of toxic reactions. Therefore, it must be used with caution while monitoring the blood concentration of cyclosporine and adjusting the dose. 4 When this product is used in combination with hydrochlorothiazide, the blood concentration of this product can be increased. 5 When used in combination with theophylline, the blood concentration of theophylline can be increased by about 13%, which can lead to toxic reactions. Therefore, the blood concentration of theophylline needs to be monitored. 6. When this product is used in combination with dicoumarol anticoagulants such as warfarin, it can enhance the anticoagulant effect of dicoumarol anticoagulants and prolong the prothrombin time, so the prothrombin time should be monitored and used with caution. 7. When this product is used in combination with phenytoin sodium, the blood concentration of phenytoin sodium can be increased, so the blood concentration of phenytoin sodium needs to be monitored.

Keep away from light and sealed. Valid for 2 years.

25mg

24 months

Jiaying Pharmaceutical (Hunan) Co., Ltd.

• Founded in:

  1995-09-13

• Address:

  No. 36, Yuanlinyu Road, Lugu Industrial Park, Changsha High-tech Development Zone

• Tax NO.:

  91430000183794893X

• Registered Funds:

  34.696987 yuan

• Website:

  Log in to view

• Email:

  Log in to view