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Ampicillin Probenecid Capsules

Function and Efficacy

Ampicillin is the bactericidal component of this product. It acts on the active reproduction stage of bacteria and inhibits the biosynthesis of cell wall mucopeptides to achieve bactericidal effects. Probenecid is a benzoic acid derivative that competes with ampicillin for the same active transporter in the renal tubules, inhibiting the latter's excretion from the renal tubules, increasing the blood concentration of ampicillin and prolonging its half-life.

Ingredients

This product is a compound preparation, its components are: ampicillin 0.1945g, probenecid 0.0555g. Chemical name: p-[(dipropylamino)sulfonyl]benzoic acid Molecular weight: C13H19NO4S

Name Description Content CAS NO. Manufacturer
AmpicillinIngredients

It acts on the active reproduction stage of bacteria and has a bactericidal effect by inhibiting the biosynthesis of cell wall mucopeptides.

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69-53-4 26
ProbenecidIngredients

Compete with ampicillin for the same active transporter in the renal tubules, inhibit the latter's excretion from the renal tubules, increase the blood concentration of ampicillin, and prolong its half-life

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57-66-9 8

Appearance

The content of this product is white powder or white crystalline powder or granules.

Indication

This product is suitable for the following infections caused by sensitive pathogenic bacteria: 1. Respiratory tract infections: upper respiratory tract infections, bacterial pneumonia, bronchitis, etc.; 2. Urinary tract infections: cystitis, urethritis, pyelonephritis, prostatitis, etc.; 3. Digestive tract infections: bacterial dysentery, etc.; 4. Ear, nose and throat infections: acute pharyngitis, tonsillitis, otitis media, sinusitis, etc.; 5. Skin and soft tissue infections; 6. Gonorrhea.

Usage and Dosage

1. Oral administration. Adults: 3 times a day, 3 capsules each time; children should follow the doctor's advice. 2. Treatment of gonorrhea: 3.5g ampicillin plus 1g probenecid (18 capsules) as a single dose.

Adverse Reactions

The adverse reactions of this product are mild, mainly including glossitis, gastritis, nausea, vomiting, enteritis, diarrhea, pseudomembranous colitis, mild abdominal pain and other gastrointestinal reactions and rashes, and occasionally transient increase in serum alanine aminotransferase (ALT).

Precautions

1. It is contraindicated for those who are allergic to the ingredients of this product and cephalosporins. 2. It is contraindicated for patients with uric acid kidney stones, acute gout attacks, and active gastrointestinal ulcers. 3. It is contraindicated for pregnant and lactating women. 4. It is contraindicated for children under 2 years old.

Special Population Medication

Precautions for children: It is forbidden for children under 2 years old. Precautions for pregnancy and lactation: The safety of this product for pregnant women has not been determined. Pregnant women should consider the pros and cons of using this product. Precautions for the elderly: Due to the decline of physiological renal function, the dosage should be appropriately reduced.

Drug Interactions

The following drugs may interact with this product when taken at the same time: allopurinol, chloramphenicol, erythromycin, sulfonamides, tetracycline, oral contraceptives, dapsone, rifampicin, anti-inflammatory drugs, methotrexate, oral hypoglycemic drugs, naproxen, salicylates, pyrazinamide, etc. If you must take the above drugs at the same time, follow the doctor's advice.

Storage

Light-proof and sealed.

Packaging Specification

0.25g (ampicillin 0.1945g and probenecid 0.0555g)

Validity Period

36 months

Manufacturer

Shenzhen Gaozhui Pharmaceutical Co., Ltd.

  • Founded in:

    1993-10-27
  • Address:

    Wulian Industrial Zone, Longgang Town, Longgang District, Shenzhen
  • Tax NO.:

    91440300618856812H
  • Registered Funds:

    10 million yuan
  • Website:

  • Email:

Other Drugs of Shenzhen Gaozhui Pharmaceutical Co., Ltd.

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