Biapenem for injection
Function and Efficacy
Biapenem is a carbapenem antibiotic that exerts its antibacterial effect by inhibiting the synthesis of bacterial cell walls. It has broad-spectrum antibacterial activity against gram-positive and gram-negative aerobic and anaerobic bacteria. Biapenem is stable to human renal dehydropeptidase I (DHP-I) and can be administered alone without the need for combination with DHP-I inhibitors.
Ingredients
Biapenem.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| BiapenemIngredients |
Biapenem is a carbapenem antibiotic that exerts its antibacterial effect by inhibiting the synthesis of bacterial cell walls. It has broad-spectrum antibacterial activity against gram-positive and gram-negative aerobic and anaerobic bacteria. Biapenem is stable to human renal dehydropeptidase I (DHP-I) and can be administered alone without the need for combination with DHP-I inhibitors. More |
120410-24-4 | 8 |
Appearance
This product is white to slightly yellowish white crystalline powder.
Indication
The strains sensitive to this product include: Staphylococcus, Streptococcus, Pneumococcus, Enterococcus (except Enterococcus faecium), Moraxella, Escherichia coli, Citrobacter, Klebsiella, Enterobacter, Serratia, Proteus, Haemophilus influenzae, Pseudomonas aeruginosa, Actinomyces, Peptostreptococcus, Bacteroides, Prevotella, Fusobacterium, etc. This product is suitable for the treatment of sepsis, pneumonia, lung abscess, secondary infection caused by chronic respiratory diseases, refractory cystitis, pyelonephritis, peritonitis, gynecological adnexitis, etc. caused by sensitive bacteria.
Usage and Dosage
Dissolve 0.3g of biapenem in 100ml of normal saline or glucose injection and drip intravenously. Adults take 0.6g per day, drip twice, 30 to 60 minutes each time. The dosage can be appropriately increased or decreased according to the patient's age and symptoms. However, the maximum daily dosage should not exceed 1.2g.
Adverse Reactions
According to foreign literature, the most common adverse reactions are rash/itching, nausea, vomiting, and diarrhea. Among 2,348 cases, 64 cases (2.7%) had adverse reactions, mainly manifested as rash (1.0%), diarrhea (0.7%), etc. Among 2,287 cases, 304 cases (13.3%) had abnormal clinical test indicators of 522, mainly manifested as increased ALT (GPT) (144 cases, 6.3%), increased AST (GOT) (93 cases, 4.1%), and increased eosinophils (77 cases, 3.4%).
Precautions
Not yet clear.
Special Population Medication
Precautions for children: The safety of the drug for children is not yet clear. Precautions for pregnancy and lactation: The safety of the drug for pregnant women is not yet clear. Precautions for the elderly: Due to the decline in physiological functions, the elderly need to pay attention to adjusting the dosage and interval of medication.
Drug Interactions
Not yet clear.
Storage
seal.
Packaging Specification
0.3g
Validity Period
12 months
Manufacturer
Simcere Pharmaceutical Co., Ltd.
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Founded in:
1998-09-10 -
Address:
No. 99, Huakang Road, Jiangbei New District, Nanjing, Jiangsu Province -
Tax NO.:
91320100135665907G -
Registered Funds:
1.60281382 million yuan -
Website:
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Email: