Barium sulfate (type II) dry suspension
Function and Efficacy
Barium salts can absorb a large amount of X-rays, and after entering the gastrointestinal tract or respiratory tract, they form a density contrast with the surrounding tissue structures on the X-ray image, thereby showing the location, contour, shape, surface structure and functional activities of these cavities. The uneven type is good for showing the fine structures of the mucosa such as the gastric cell.
Ingredients
Main ingredients and chemical names of this product: The main ingredient of this product is barium sulfate type II, and its chemical name is barium sulfate. This product is a dry suspension prepared by adding appropriate dispersants and flavoring agents to barium sulfate (type II). Molecular formula: BaSO4 Molecular weight: 233.39
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Barium sulfateIngredients |
Barium salts can absorb a large amount of X-rays, and after entering the gastrointestinal tract or respiratory tract, they form a density contrast with the surrounding tissue structures on the X-ray image, thereby showing the location, contour, shape, surface structure and functional activities of these cavities. The uneven type is good for showing the fine structures of the mucosa such as the gastric cell. More |
7727-43-7 | 1 |
Appearance
This product is white loose fine powder with fragrance and uneven particle diameter.
Indication
Barium sulfate dry suspension is suitable for single and double contrast examinations of the esophagus, stomach, duodenum, small intestine, and colon.
Usage and Dosage
Commonly used introduction methods include oral administration, small intestinal enema and colonic enema. 1. Esophageal examination: Oral barium [concentration 60~250% (W/V)] 15~60ml, the esophagus and its peristalsis can be observed immediately; before taking the barium, take gas-producing drugs first, and the esophagus can be double-contrast examined. 2 Double contrast examination of stomach and duodenum: fast for more than 6 hours, take gas-producing drugs orally, and after 300~500ml of CO2 gas is produced in the stomach, you can first take 70~100ml of barium [concentration 200~250% (W/V), viscosity 150~300 mPas] orally, and let the patient turn over several times to allow the barium to be evenly coated on the gastric mucosa. If necessary, take another 150ml of barium; if 20 minutes before the contrast examination, give the patient hypotonic drugs (such as injection of scopolamine, or oral atropine, etc.), and take oral gastric enzymes to clean the gastric juice, and then perform double contrast examination, the surface structure of the gastric mucosa can be displayed more clearly. 3 Gastrointestinal single contrast follow-up examination: After fasting for more than 6 hours, take 240-480 ml of 40-120% (W/V) barium orally, and the morphology and peristalsis of the stomach and duodenum can be observed immediately; the morphology and peristalsis of the small intestine can be observed after 15-30 minutes; the morphology and peristalsis of all small intestines can be observed after 1.5 hours; the ileocecal region and the right half of the large intestine can be observed after 2-6 hours. 4 Small intestine enema examination: After fasting for 8-12 hours, 800-2400 ml of 30-80% (W/V) barium is directly introduced into the duodenum or proximal jejunum through a special catheter, and small intestine examination is performed segment by segment. If necessary, double contrast examination can be performed directly instead of single contrast examination. 5 Colon enema examination: Eat liquid or semi-liquid food 1-3 days before the examination, use appropriate amount of laxatives when necessary, and clean the intestines 1-2 hours before the examination. Insert the tube into the colon through the anus, and inject contrast agent to fill the entire large intestine for contrast imaging. After injecting barium with a concentration of 20-60% (W/V), fluoroscopy and radiography are performed, which is single contrast imaging; then most of the barium is discharged, and gas is injected to fill the large intestine, which is double contrast imaging. When performing direct colon double contrast imaging, 150-300ml of barium with a concentration of 60-80% (W/V) is first injected through the catheter, and the body position is turned and gas is injected so that the barium and gas fill the entire large intestine, and double contrast imaging is performed. In order to achieve good results, hypotonic drugs such as glucagon or scopolamine are often injected intramuscularly or intravenously before injecting contrast agents.
Adverse Reactions
Oral administration of barium can cause symptoms such as nausea, constipation, and diarrhea; improper use can also cause intestinal perforation, followed by peritonitis, adhesions, and granulomas, which can even be fatal in severe cases. When a large amount of barium enters the lungs, it can cause mechanical stimulation and inflammatory reactions, causing infiltration of foreign body giant cells, epithelial cells, and monocytes in the early stages, and later fibrosis around the deposited barium inflammation, forming barium nodules.
Precautions
This product is contraindicated for oral gastrointestinal examination in the following situations: 1. Acute gastrointestinal perforation 2. Esophageal tracheal fistula and suspected congenital esophageal atresia 3. Recent rupture of esophageal veins and massive bleeding 4. Colon obstruction 5. Pharyngeal paralysis.
Special Population Medication
Precautions for children: Esophageal contrast: Mix a small amount into a paste and swallow. Gastrointestinal contrast: Mix 100-200g of this product with 200-500ml of water and take. Barium enema: Mix 200g of this product with 1000ml of water and take. Precautions for pregnancy and lactation: Prevented to use during pregnancy. There is no data on the safety of the drug for lactating women.
Drug Interactions
High atomic weight drugs such as bismuth and calcium preparations are prohibited 3 days before the examination; drugs that may affect the gastrointestinal tract such as atropine, antacids and laxatives are prohibited 1 day before the examination.
Storage
Keep tightly closed.
Packaging Specification
200g; 300g
Validity Period
36 months