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Sulbenicillin Sodium for Injection

Function and Efficacy

Sulbenzyl penicillin is a broad-spectrum semi-synthetic penicillin antibiotic. It has antibacterial effects on Enterobacteriaceae such as Escherichia coli, Proteus, Enterobacter, Citrobacter, Salmonella and Shigella, as well as other Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae and Neisseria. This product also has antibacterial activity against hemolytic streptococci, Streptococcus pneumoniae and non-penicillinase-producing Staphylococci. This product also has a certain effect on anaerobic bacteria including Peptostreptococci and Clostridium. The mechanism of action of sulbenzyl penicillin is to exert a bactericidal effect by inhibiting bacterial cell wall synthesis.

Ingredients

Sulbenicillin Sodium

Name Description Content CAS NO. Manufacturer
Sulbenicillin sodiumIngredients

Sulbenzyl penicillin is a broad-spectrum semi-synthetic penicillin antibiotic. It has antibacterial effects on Enterobacteriaceae such as Escherichia coli, Proteus, Enterobacter, Citrobacter, Salmonella and Shigella, as well as other Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae and Neisseria. This product also has antibacterial activity against hemolytic streptococci, Streptococcus pneumoniae and non-penicillinase-producing Staphylococci. This product also has a certain effect on anaerobic bacteria including Peptostreptococci and Clostridium. The mechanism of action of sulbenzyl penicillin is to exert a bactericidal effect by inhibiting bacterial cell wall synthesis.

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28002-18-8 7

Appearance

This product is white or light yellow freeze-dried powder.

Indication

It is mainly suitable for pneumonia, urinary tract infection, complicated skin and soft tissue infection and sepsis caused by Pseudomonas aeruginosa, some Proteus and other sensitive Gram-negative bacteria that are sensitive to this product. Abdominal infection and pelvic infection caused by bacteria that are sensitive to this product should be used in combination with anti-anaerobic drugs.

Usage and Dosage

Intravenous drip or intravenous injection; the daily dose for adults with moderate infection is 8g. In severe infection or Pseudomonas aeruginosa infection, the dose needs to be increased to 20g per day, administered intravenously in 4 divided doses; for children, the daily dose is 80-300mg/kg per body weight, administered in 4 divided doses, depending on the condition.

Adverse Reactions

1. Allergic reactions are common, including rash, fever, etc.; anaphylactic shock is rare. Once it occurs, emergency treatment must be given on the spot, including maintaining airway patency, oxygen inhalation, and administration of epinephrine, glucocorticoids and other treatment measures; 2. Gastrointestinal reactions such as nausea and vomiting; 3. Abnormal laboratory tests include leukopenia or neutropenia, transient increase in serum transaminase, etc.

Precautions

Contraindicated in patients with a history of allergy to penicillins or a positive penicillin skin test

Special Population Medication

Precautions for children: See [Usage and Dosage]. Precautions for pregnancy and lactation: There is no safety data for the use of this product by pregnant women. Pregnant women should use this product only when it is necessary. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

Drug Interactions

Not yet clear.

Storage

Keep away from light, tightly closed, in a cool and dry place.

Packaging Specification

1.0g (1 million units)

Validity Period

24 months

Manufacturer

Reyoung Pharmaceutical Co., Ltd.

  • Founded in:

    1998-03-20
  • Address:

    No. 1, Ruiyang Road, Yiyuan County, Shandong Province
  • Tax NO.:

    913703001686121827
  • Registered Funds:

    366.74 million yuan
  • Website:

  • Email:

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