Betamethasone Sodium Phosphate Injection

Adrenal cortex hormone drugs. They have multiple pharmacological effects such as anti-inflammatory, anti-allergic and immunosuppressive. 1 Anti-inflammatory effect: Glucocorticoids reduce and prevent tissue response to inflammation, thereby reducing the manifestation of inflammation. 2 Immunosuppressive effect: prevent or inhibit cell-mediated immune response, delayed allergic reaction, and reduce the expansion of primary immune response. 3 Anti-toxic and anti-shock effect: Glucocorticoids can counteract the stimulation of bacterial endotoxins on the body, reduce cell damage, and play a role in protecting the body.

16β-methyl-11β,17a,21-trihydroxy-9a-fluoro-pregna-1,4-diene-3,20-dione-21-phosphate disodium salt.

This product is a colorless clear liquid.

It is mainly used for allergic and autoimmune inflammatory diseases. It is now mostly used for active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, etc. It is also used for the comprehensive treatment of certain infections.

Intramuscular or intravenous injection: 2-20 mg per day, divided into two doses.

There are no obvious adverse reactions when glucocorticoids are used in physiological dose replacement therapy. Adverse reactions mostly occur when pharmacological doses are used, and are closely related to the course of treatment, dosage, type of medication, usage and route of administration. Common adverse reactions are as follows: 1. Long-term use may cause the following side effects: iatrogenic Cushing's syndrome facial and body shape, weight gain, lower limb edema, purple lines, easy bleeding tendency, poor wound healing, acne, menstrual disorders, avascular necrosis of the humeral or femoral head, osteoporosis and fractures (including vertebral compression fractures, pathological fractures of long bones), muscle weakness, muscle atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), pancreatitis, peptic ulcer or perforation, growth inhibition in children, glaucoma, cataracts, benign cranial

Patients who are allergic to this product and other steroid hormones are prohibited from using it. Patients with the following diseases should not use it in general. In special cases, the pros and cons should be weighed, but attention should be paid to the possibility of worsening of the condition: severe mental illness (past or present) and epilepsy, active peptic ulcer disease, recent gastrointestinal anastomosis, fractures, wound repair period, corneal ulcer, hyperadrenocortical syndrome, hypertension, diabetes, pregnant women, infections that cannot be controlled by antibacterial drugs such as chickenpox, measles, fungal infections, severe osteoporosis, etc.

1. Nonsteroidal anti-inflammatory analgesics can enhance its ulcerogenic effect. 2. It can enhance the hepatotoxicity of acetaminophen. 3. When used in combination with amphotericin B or carbonic anhydrase inhibitors, it can aggravate hypokalemia. Long-term use with carbonic anhydrase inhibitors can easily lead to hypocalcemia and osteoporosis. 4. When used in combination with protein anabolic hormones, it can increase the incidence of edema and aggravate acne. 5. Long-term use with anticholinergics (such as atropine) can cause increased intraocular pressure. 6. Tricyclic antidepressants can aggravate the mental symptoms caused by them. 7. When used in combination with hypoglycemic drugs such as insulin, it can increase the blood sugar level in diabetic patients.

Keep in a dark place and sealed. Valid for 24 months

1ml:2mg (in terms of betamethasone)

Shandong Shenglu Pharmaceutical Co., Ltd.

• Founded in:

  2001-12-27

• Address:

  North end of Sihe Road, Sihe Office, Sishui County

• Tax NO.:

  91370831678104460B

• Registered Funds:

  1.2 million yuan

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