Sodium Cantharidate Injection
Function and Efficacy
1. Pharmacological experiments show that sodium cantharidinate can directly enter the nucleus and nucleolus of mouse ascites liver cancer cells. It inhibits the content of DNA and RNA in cancer cells and the infiltration of precursors, proving that it acts on the nucleic acid metabolism of cancer cells, which in turn changes the morphology and function of cancer cells and kills cancer cells. This product can reduce the activity of CANP phosphodiesterase in tumor cells and increase the activity of catalase. This product can also stimulate the bone marrow hematopoietic system and increase white blood cells. 2. Toxicology The results of acute toxicity, hemolysis and irritation tests of this product are: the D50 of intravenous injection of mice is 4.16 mg/kg. The D50 of intraperitoneal injection of mice is 4.39 mg/kg. There is no in vitro hemolysis reaction. It is mildly irritating to rabbit eyes. It has no irritating effect on rabbit and mouse muscles.
Ingredients
The main ingredient and chemical name of this product is sodium cantharidin. Structural formula: Molecular formula: C10H12Na2O5 Molecular weight: 258.1
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CANTHARIDIC ACIDIngredients |
It can directly enter the nucleus and nucleolus of mouse ascites liver cancer cells, inhibit the content of DNA and RNA in cancer cells and the infiltration of precursors, act on the nucleic acid metabolism of cancer cells, change the morphology and function of cancer cells, and kill cancer cells; it can reduce the activity of CANP phosphodiesterase in tumor cells and increase the activity of catalase; it can stimulate the bone marrow hematopoietic system and increase white blood cells. More |
28874-45-5 | 1 |
Appearance
This product is a colorless clear liquid.
Indication
Anti-tumor drug. Used for primary liver cancer and other tumors and leukopenia. Also used for hepatitis, cirrhosis and hepatitis B virus carriers.
Usage and Dosage
Intravenous drip: Once a day, 2-10 ml each time, diluted with 0.9% sodium chloride or 5%-10% glucose injection and then dripped.
Adverse Reactions
Some patients may experience urinary irritation, and redness, swelling, pain, and tenderness may occasionally occur during local intravenous injection.
Precautions
Not yet clear.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not for use by pregnant and lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
2ml:0.1mg
Validity Period
Tentative 24 months
Manufacturer
Guizhou Jinqiao Pharmaceutical Co., Ltd.
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Founded in:
2003-03-25 -
Address:
No. 179, Chuangbei Road, Shawen Ecological Technology Industrial Park, Guiyang National High-tech Industrial Development Zone, Guiyang City, Guizhou Province -
Tax NO.:
91520100745727642R -
Registered Funds:
13.785396 yuan -
Website:
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Email: