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Metronidazole benzoate dispersible tablets

Function and Efficacy

This product has antibacterial effects on the following obligate anaerobes. Gram-negative anaerobic bacilli: Bacteroides fragilis, Bacteroides vulgaris, Bacteroides gibbsii, Bacteroides ovale, Bacteroides polymorpha, etc. and Fusobacterium. Gram-positive anaerobic bacilli: Eubacterium, Clostridium. Gram-positive anaerobic cocci: Peptococcus and Peptostreptococcus. This product has strong activity against protozoa, such as Trichomonas vaginalis; it has activity against amoeba and Lambertella. The animal mode of action is to cut off the DNA chain and inhibit DNA synthesis, thereby interfering with and interrupting the growth and reproduction of anaerobic microorganisms.

Ingredients

The main ingredient is metronidazole benzoate.

Name Description Content CAS NO. Manufacturer
BenzoylmetronildazoleIngredients

It has antibacterial effects on obligate anaerobes, including Gram-negative anaerobic rods (such as Bacteroides and Fusobacterium) and Gram-positive anaerobic rods and cocci (such as Eubacterium, Clostridium, Peptococcus and Peptostreptococcus). It is active against protozoa (such as Trichomonas vaginalis), ameba and Lambda. The animal mode of action is to cut DNA chains and inhibit DNA synthesis, thereby interfering with and interrupting the growth and reproduction of anaerobic microorganisms.

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13182-89-3 8

Appearance

This product is off-white tablets.

Indication

This product can be used for: 1. Urogenital trichomoniasis, such as vaginal trichomoniasis, etc.; 2. Intestinal and extraintestinal amebiasis, such as amebiasis and amoebic liver abscess, etc.; 3. Giardiasis; 4. Various infections caused by sensitive anaerobic bacteria, such as bacteremia, septicemia, abdominal postoperative infection, etc.; 5. Prevention of gynecological and surgical postoperative infections caused by anaerobic bacteria.

Usage and Dosage

This product is a dispersible tablet that can be taken directly orally/swallowed, or put an appropriate amount of this product into about 100ml of water, shake and disperse it, and then take it orally. Take it one hour before meals. The dosage for adults and children over 12 years old is as follows: 1. Treatment of sensitive anaerobic bacterial infections: 0.64g (2 tablets) 3 times a day, each time, for 7 consecutive days. 2. As a preventive medication: start taking it 24 hours before surgery, the dose is 0.64g (2 tablets) each time, for 7 consecutive days. 3. Amebiasis: (1) Intestinal amebiasis: 1.28g (4 tablets) 3 times a day each time, for 5 consecutive days. (2) Chronic amoebic hepatitis: 0.64g (2 tablets) 3 times a day each time, for 5-10 consecutive days. (3) Amebic liver abscess and other forms of extraintestinal amebiasis: 0.64g (2 tablets) 3 times a day each time, for

Adverse Reactions

Occasionally, there have been reports of bad breath, tongue coating and gastrointestinal discomfort, drowsiness, dizziness, headache, ataxia, rash, itching, ataxia, dark urine (caused by metabolism), etc., but they are extremely rare. A few cases of peripheral nervous system problems have been reported in high doses or long-term treatment.

Precautions

1. People who are allergic to this product are prohibited from using it. 2. Pregnant and lactating women are prohibited from using it. 3. People with active central nervous system diseases and blood diseases are prohibited from using it.

Special Population Medication

Precautions for children: Not clear. Precautions for pregnancy and lactation: Contraindicated for pregnant and lactating women. Precautions for the elderly: Pay attention to liver function.

Drug Interactions

1. This product can enhance the anticoagulant effect of warfarin and other drugs. 2. Oxytetracycline can interfere with the effect of this product in eliminating vaginal Trichomonas.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.32g

Validity Period

24 months

Manufacturer

Jiangsu Morning Brand Pharmaceutical Group Co., Ltd.

  • Founded in:

    1996-05-28
  • Address:

    No. 666, Beijing East Road, Haimen District, Nantong City, Jiangsu Province
  • Tax NO.:

    913206001388073171
  • Registered Funds:

    55 million yuan
  • Website:

  • Email:

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