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Imiquimod cream

Function and Efficacy

Imiquimod is a small molecule immunomodulator belonging to the imidazoquinoline class of compounds. Its mechanism of action in treating external genital/perianal warts is still unclear. This product does not have direct antiviral activity, nor does it cause direct, non-specific cell lysis and destruction. However, preclinical studies suggest that this product may produce antiviral activity by inducing cytokines in the body, including INF-α. The clinical relevance of these findings is still unclear.

Ingredients

The main ingredients of this product are: Imiquimod

Name Description Content CAS NO. Manufacturer
ImiquimodIngredients

Imiquimod is a small molecule immunomodulator belonging to the imidazoquinoline class of compounds. Its mechanism of action in treating external genital/perianal warts is still unclear. This product does not have direct antiviral activity, nor does it cause direct, non-specific cell lysis and destruction. However, preclinical studies suggest that this product may produce antiviral activity by inducing cytokines in the body, including INF-α. The clinical relevance of these findings is still unclear.

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Appearance

This product is a white or off-white cream.

Indication

Imiquimod topical cream is used to treat genital warts/condyloma acuminatum on the anus and genitals in adults.

Usage and Dosage

Wash your hands before going to bed, then open the package, squeeze the imiquimod ointment on your fingers, apply the ointment thinly on the surface of the wart, gently massage to make the ointment penetrate, discard the bag after application, and wash your hands. 5% imiquimod cream, 3 times a week (apply every other day), once before going to bed, one bag each time, until the wart disappears or up to 16 weeks.

Adverse Reactions

Local skin reactions such as erythema, erosion, exfoliation/flaking and edema are very common. Once severe skin reactions occur, the application site should be washed off with weak alkaline soap and water. After the skin reaction recovers, 5% imiquimod cream can be reapplied. A small number of patients also have systemic reactions such as myalgia, flu-like symptoms, headache, diarrhea, etc., which are mild and moderate.

Precautions

1. Allergic to imiquimod or excipients; 2. Not recommended for HPV infection in the urethra, vagina, cervix, rectum or anus; 3. It is not recommended to use 5% imiquimod cream immediately after other medications or surgical treatments; it is also not recommended to use 5% imiquimod cream in combination with other drugs for the treatment of genital warts.

Special Population Medication

Precautions for children: There is no experience of using the drug in patients under 18 years old. Precautions for pregnancy and lactation: 1. It is not recommended for pregnant women to use this product. 2. It is not known whether the drug is secreted in breast milk after topical application of imiquimod. It is not recommended for lactating women to use this product. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

Drug Interactions

This experiment has not been conducted and there are no reliable references.

Storage

Keep away from light and store in a sealed container below 25°C.

Packaging Specification

(0.25g:12.5mg)*12 bags

Validity Period

24 months.

Manufacturer

Topfond Pharmaceutical Co., Ltd.

  • Founded in:

    2013-11-13
  • Address:

    No. 2 Guangming Road, Yicheng District, Zhumadian City
  • Tax NO.:

    91411700083473072R
  • Registered Funds:

    420 million yuan
  • Website:

  • Email:

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