Imiquimod cream

1 Pharmacodynamics Imiquimod belongs to the class of imidazoquinoline compounds. It is a small molecule immunomodulator. Its mechanism of action in the treatment of external genital/perianal warts is still unclear. This product does not have direct antiviral activity, nor does it cause direct, non-specific cytolytic destruction. However, preclinical studies suggest that this product may produce antiviral activity by inducing cytokines in the body, including INF-α. The clinical relevance of these findings is still unclear. 2 Toxicology Rats and mice were administered skin administration 3 times a week for 4 months. Rats at 0.5 and 2.5 mg/kg showed weight loss and increased spleen weight. Local skin irritation (severe erythema, mild to moderate edema, peeling, and crusting) was more severe than that observed in humans.

The main ingredient and chemical name of this product are: 1-(2-methylpropyl)-1H-imidazo[4,5-C]quinolin-4-amine

This product is a white cream with an emulsion base

Imiquimod topical cream 5% is used to treat genital and anal warts/condyloma acuminatum in adults

Wash your hands before going to bed, then open the package, squeeze the imiquimod ointment on your fingers, apply the ointment thinly on the surface of the wart, gently massage to make the ointment penetrate, discard the bag after application, and wash your hands. 5% imiquimod cream, 3 times a week (apply every other day), once before going to bed, one bag each time, until the wart disappears or up to 16 weeks.

Local skin reactions such as erythema, erosion, exfoliation/flaking and edema are very common. Once severe skin reactions occur, the application site should be washed off with weak alkaline soap and water. After the skin reaction recovers, 5% imiquimod cream can be reapplied. A small number of patients also have systemic reactions such as myalgia, flu-like symptoms, headache, diarrhea, etc., which are mild and moderate.

1. Allergic to imiquimod or excipients; 2. Not recommended for HPV infection in the urethra, vagina, cervix, rectum or anus; 3. It is not recommended to use 5% imiquimod cream immediately after other medications or surgical treatments; it is also not recommended to use 5% imiquimod cream in combination with other drugs for the treatment of genital warts.

Precautions for children: The safety and efficacy of this product in patients under 18 years of age have not been established. Precautions for pregnancy and lactation: 1. This product is not recommended for pregnant women. 2. It is not known whether the drug is secreted in breast milk after topical application of imiquimod. This product is not recommended for lactating women. Precautions for the elderly: The safety and efficacy data of this product for elderly patients have not been established.

Not clear yet.

Store below 25℃ and avoid freezing. Valid for one year

0.25g:12.5mg

24 months.

Topfond Pharmaceutical Co., Ltd.

• Founded in:

  2013-11-13

• Address:

  No. 2 Guangming Road, Yicheng District, Zhumadian City

• Tax NO.:

  91411700083473072R

• Registered Funds:

  420 million yuan

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