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Fusultiamine Injection

Function and Efficacy

This product is a vitamin drug. Fursultiamine is a new derivative of vitamin B1. It is quickly converted into active thiamine in the body and is not decomposed by thiaminase in the body. It has strong affinity for tissues, high concentration in organs, high concentration in blood, and long maintenance time. It has the characteristics of high efficiency, long-term effect and low toxicity. Like vitamin B1, active thiamine combines with pyrophosphate in the body to form a coenzyme. It participates in the oxidative decarboxylation reaction of pyruvate and a-ketoglutaric acid in sugar metabolism and is necessary for sugar metabolism. When it is deficient, oxidation is blocked to form pyruvate, lactic acid accumulates, and affects the body's energy supply. Its symptoms are mainly manifested in the nervous and cardiovascular systems, and multiple peripheral neuritis affecting both sensory nerves and motor nerves occurs, manifested as paresthesia, neuralgia, limb weakness, and muscle soreness and atrophy. In terms of cardiovascular, due to the increase of acetone and lactic acid in the blood, the arterioles are dilated, the diastolic pressure decreases, and the myocardial metabolism is disturbed, so it is easy to have symptoms of heart failure such as palpitations, shortness of breath, chest tightness, cardiac hypertrophy, liver and lung congestion and peripheral edema. Digestive tract symptoms include decreased appetite leading to weakness and weight loss.

Ingredients

Fursultiamine

Name Description Content CAS NO. Manufacturer
FursultiamineIngredients

This product is a vitamin drug. Fursultiamine is a new derivative of vitamin B1. It is quickly converted into active thiamine in the body and is not decomposed by thiaminase in the body. It has strong affinity for tissues, high concentration in organs, high concentration in blood, and long maintenance time. It has the characteristics of high efficiency, long-term effect and low toxicity. Like vitamin B1, active thiamine combines with pyrophosphate in the body to form coenzyme, participates in the oxidative decarboxylation reaction of pyruvate and a-ketoglutaric acid in sugar metabolism, and is necessary for sugar metabolism. When it is deficient, oxidation is blocked to form pyruvate, lactic acid accumulates, and affects the body's energy supply. Its symptoms are mainly manifested in the nervous and cardiovascular systems, and multiple peripheral neuritis affecting both sensory nerves and motor nerves occurs, manifested as paresthesia, neuralgia, limb weakness, and muscle soreness and atrophy. In terms of cardiovascular, due to the increase of acetone and lactic acid in the blood, the small arteries are dilated, the diastolic pressure decreases, and the myocardial metabolism is disturbed, so it is easy to have symptoms of heart failure such as palpitations, shortness of breath, chest tightness, cardiac hypertrophy, liver and lung congestion and peripheral edema. Digestive tract symptoms include decreased appetite leading to weakness and weight loss.

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Appearance

This product is a colorless or slightly yellow clear liquid.

Indication

It is suitable for the treatment of beriberi or Wernicke's encephalopathy caused by vitamin B1. It can also be used as an auxiliary treatment for peripheral neuritis and indigestion caused by vitamin B1 deficiency.

Usage and Dosage

Intramuscular injection: 20-40 mg per day.

Adverse Reactions

Occasionally, dizziness, fatigue, nausea, and vomiting occur, which disappear after stopping the drug; hard masses occasionally occur at the injection site, which gradually disappear after hot compresses or stopping the drug. Allergic reactions occur occasionally.

Precautions

Dizziness, fatigue, nausea, and vomiting may occur occasionally, which will disappear after stopping the medication. Hard lumps may occur occasionally at the injection site, which will gradually disappear after hot compresses or stopping the medication.

Drug Interactions

This product is easily decomposed in alkaline solution and may deteriorate when combined with alkaline drugs such as sodium bicarbonate and sodium citrate.

Storage

Keep away from light, tightly closed, in a cool place.

Packaging Specification

2 ml: 20 mg

Manufacturer

Suzhou Pharmaceutical Factory

  • Founded in:

    2006-02-14
  • Address:

    No. 2-1, Dongwu South Road, Wuzhong District, Suzhou City
  • Tax NO.:

    91320506138170408U
  • Registered Funds:

    -
  • Website:

  • Email:

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