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Naftifine Ketoconazole Cream

Function and Efficacy

Ketoconazole is an azole antifungal drug. It has antibacterial and bactericidal effects on dermatophytes, yeasts (Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi and Fungi; except for Entomophthora, it has weaker effects on Aspergillus, Schenckia, some Phaeochromocytaceae and Mucor. The mechanism of action of ketoconazole is mainly to highly selectively interfere with the activity of fungal cytochrome P-450, thereby inhibiting the biosynthesis of ergosterol on the fungal cell membrane. Clobetasol propionate is a potent topical corticosteroid. It acts quickly and has strong capillary constriction and anti-inflammatory effects. Neomycin sulfate belongs to the aminoglycoside antibiotics and can be used externally to treat local infections.

Ingredients

This product is a compound preparation, and its components are: every 10g of naftifine hydrochloride cream contains 0.1g of naftifine hydrochloride and 25mg of ketoconazole.

Name Description Content CAS NO. Manufacturer
Naftifine hydrochlorideIngredients

No specific pharmacological effects mentioned

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65473-14-5 7
KetoconazoleIngredients

It has antibacterial and bactericidal effects on dermatophytes, yeasts (Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi and Fungi; except for Entomophthora, it has weaker effects on Aspergillus, Schenckia, some Phaeophyceae, and Mucor. The mechanism of action of ketoconazole is mainly to highly selectively interfere with the activity of fungal cytochrome P-450, thereby inhibiting the biosynthesis of ergosterol on the fungal cell membrane.

More
65277-42-1 25

Appearance

This product is a white ointment with an emulsion base.

Indication

This product is suitable for the treatment of fungal skin diseases, such as tinea manuum, tinea pedis, tinea corporis, tinea capitis, and cutaneous candidiasis.

Usage and Dosage

For external use, apply evenly to the affected area and surrounding skin, 1 to 2 times a day. The course of treatment is generally 2 to 4 weeks.

Adverse Reactions

This product is well tolerated for external use. A small number of patients may experience mild local irritation symptoms such as burning, stinging, dry skin, erythema, itching, and occasionally allergic reactions may occur, causing contact dermatitis.

Precautions

This product is contraindicated for patients who are allergic to any active ingredient or excipient in this product or other imidazole drugs.

Special Population Medication

Precautions for children: There is currently a lack of detailed research data. Precautions for pregnancy and lactation: There is no trial or literature data on the topical use of naftifine cream by pregnant and lactating women. Pregnant and lactating women should use this product with caution after weighing the pros and cons. Lactating women should stop breastfeeding when using this product. Precautions for the elderly: There is currently a lack of detailed research data.

Drug Interactions

There is currently a lack of detailed research data.

Storage

seal.

Packaging Specification

10g: 0.1g naftifine hydrochloride and 25mg ketoconazole; 15g: 0.15g naftifine hydrochloride and 37.5mg ketoconazole

Validity Period

Tentative 24 months

Manufacturer

Chongqing Huapont Pharmaceutical Co., Ltd.

  • Founded in:

    2012-06-26
  • Address:

    No. 69, Renhe Xingguang Avenue, Yubei District, Chongqing
  • Tax NO.:

    915000005992299001
  • Registered Funds:

    450 million yuan
  • Website:

  • Email:

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