Naftifine hydrochloride
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Naftifine hydrochloride
structure -
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CAS No:
65473-14-5
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Formula:
C21H21N.ClH
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Chemical Name:
Naftifine hydrochloride
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Synonyms:
1-Naphthalenemethanamine,N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-,hydrochloride (1:1);1-Naphthalenemethanamine,N-methyl-N-(3-phenyl-2-propenyl)-,hydrochloride,(E)-;1-Naphthalenemethanamine,N-methyl-N-[(2E)-3-phenyl-2-propenyl]-,hydrochloride;Naftifine hydrochloride;Exoderil;Naftin;AW 105-843;SN 105-843
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Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs
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CAS No:
Description
Naftifine Hydrochloride is a synthetic, broad spectrum, antifungal agent.Target: AntifungalNaftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains; minimal inhibitory concentration (MIC) range 0.1 to 0.2 mg/mL), aspergilli (6 strains; MIC range, 0.8 to 12.5 mg/mL), Sporothrix schenckii (2 strains; MICs, 0.8 and 1.5 mg/mL), and yeasts of the genus Candida (77 strains; MIC range, 1.5 to greater than 100 mg/mL) [1]. The MIC of naftifine for C. albic
Characteristics
3.2
5.78700
177 °C
440.1ºC at 760 mmHg
194.4ºC
ethanol: soluble 50mg/mL
-20°C Freezer
Safety Information
NONH for all modes of transport
nwg
24/25
QJ8650000
P260, P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P314, P321, P330, P333+P313, P363, P391, P501
H302
Drug Function and Efficacy
Extract from the above information
Registered Holders
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NOVARTIS PHARMA AG
Active
Brazil
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OLON S.P.A.
Active
Italy
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Chongqing Shengkai Pharmaceutical Co., Ltd.
Active
China
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