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Acitretin Capsules

Function and Efficacy

This product has the functions of regulating epidermal cell differentiation and proliferation, but its mechanism of action on psoriasis and other keratotic skin diseases is still unclear.

Ingredients

The main ingredient of this product is acitretin, whose chemical name is all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid

Name Description Content CAS NO. Manufacturer
AcitretinIngredients

It has the functions of regulating epidermal cell differentiation and proliferation, but its mechanism of action on psoriasis and other keratotic skin diseases is still unclear.

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55079-83-9 7

Appearance

This product is a capsule, and the contents are yellow granules and powder.

Indication

This product is used to treat the following diseases: 1. Severe psoriasis, including erythrodermic psoriasis, pustular psoriasis, etc. 2. Other keratotic skin diseases.

Usage and Dosage

This product has large individual differences, and the dosage needs to be individualized to achieve the maximum clinical therapeutic effect with the minimum adverse reactions. Initial treatment: The initial dose of Acitretin should be 25 or 30 mg per day, taken as a single dose with the main meals. If the treatment effect is not satisfactory after 4 weeks and there are no toxic reactions, the maximum daily dose can be gradually increased to 75 mg per day. If side effects need to be minimized, this dose can be reduced. Maintenance treatment: After the treatment begins to be effective, a maintenance dose of 25 mg to 50 mg per day can be given. The maintenance dose should be based on clinical effect and tolerability. In some cases, it may be necessary to increase the dose to a maximum of 75 mg per day. In general, treatment should be stopped when the skin lesions have sufficiently subsided. Relapses can be treated again according to the initial treatment method.

Adverse Reactions

1 The main and common adverse reactions of this product are vitamin A hypersensitivity syndrome-like reactions, which are mainly manifested as: (1) Skin: itching, hyperesthesia, photosensitivity, erythema, dryness, scaling, paronychia, etc. (3) Eyes: dry eyes, conjunctivitis, etc. (4) Musculoskeletal: myalgia, back pain, joint pain, bone hyperplasia, etc. (5) Nervous system: headache, abnormal gait, increased intracranial pressure, tinnitus, earache, etc. (6) Others: fatigue, anorexia, change in appetite, nausea, abdominal pain, etc. (7)

Precautions

1. Pregnant women, lactating women and women who want to have children within two years are prohibited from using this product. 2. People who are allergic to acitretin or other retinoids are prohibited from using this product. 3. People with severe liver and kidney dysfunction, hyperlipidemia, hypervitaminosis A or allergic to vitamin A and its metabolites are prohibited from using this product.

Special Population Medication

Precautions during pregnancy and lactation: Pregnant women, lactating women and women who wish to have children within two years are prohibited from using this product.

Drug Interactions

This product should not be used with tetracycline, methotrexate, vitamin A and other retinoid drugs to avoid side effects.

Storage

Sealed and stored in a cool dark place.

Packaging Specification

25mg

Validity Period

24 months

Manufacturer

Chongqing Huapont Pharmaceutical Co., Ltd.

  • Founded in:

    2012-06-26
  • Address:

    No. 69, Renhe Xingguang Avenue, Yubei District, Chongqing
  • Tax NO.:

    915000005992299001
  • Registered Funds:

    450 million yuan
  • Website:

  • Email:

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