Sodium Alginate Diester and Sodium Chloride Injection

Sodium alginate is a polysaccharide compound obtained by introducing effective groups and refining seaweed extract as the basic raw material. It belongs to the class of heparin drugs. Sodium alginate has the characteristics of anionic polyelectrolyte fiber structure, which can concentrate charges along the chain. Under the action of its electric repulsion, the surface of cells rich in negative charges can enhance the mutual repulsion, so it can resist the adhesion between red blood cells and between red blood cells and blood vessel walls, significantly reduce blood viscosity, and improve microcirculation. In addition, sodium alginate can inactivate thrombin, inhibit platelet aggregation caused by damage to the vascular endothelium, adenosine diphosphate (ADP) and thrombin activation, and has an anticoagulant effect. After the application of sodium alginate, the content of total cholesterol, triglycerides and low-density lipoprotein (LDL) in plasma can be reduced, and the level of high-density lipoprotein (HDL) can be increased. It has the effect of lowering blood lipids.

The main ingredient of this product is sodium alginate, which is a polysaccharide compound made from seaweed extract.

This product is a colorless or almost colorless clear liquid.

Ischemic heart and cerebrovascular diseases (cerebral thrombosis, cerebral embolism, coronary heart disease, etc.) and hyperlipidemia.

Intravenous drip. For adults, 1-3 mg/kg per time according to body weight, drip slowly (drip rate should not exceed 0.75 mg/kg/hour), once a day. The maximum daily dose should not exceed 150 mg.

The incidence of adverse reactions is 5% to 23%, mainly manifested as: 1. Adverse reactions of the circulatory system: mainly manifested as palpitations, angina pectoris, hypotension and abnormal electrocardiogram. 2. Adverse reactions of the blood system: leukopenia, thrombocytopenia, bleeding in the gums, uterus or conjunctiva, and there are also reports of cerebral hemorrhage and upper gastrointestinal bleeding and shock. 3. Adverse reactions of the digestive system: mainly manifested as dry mouth, nausea, vomiting, diarrhea, abdominal pain, constipation and poor appetite; sometimes liver abnormalities occur, manifested as increased TTT or ALT. 4. Allergic reactions: skin redness, itching, rash, annular erythema, exfoliative dermatitis, limb venous dilatation and peripheral neurologic edema of the extremities, acute laryngeal edema and anaphylactic shock. 5. Adverse reactions of the nervous system: headache, dizziness, drowsiness, irritability, etc. 6. Other adverse reactions: fatigue, fever, joint and muscle pain, hearing loss and hair loss.

It is contraindicated for patients with bleeding diseases or bleeding tendency, or severe liver or kidney dysfunction.

Sodium alginate diester is an acidic mucopolysaccharide compound and should not be used in combination with other drugs to avoid incompatibility.

Keep in a sealed container and away from light.

100ml: 0.1g sodium alginate and 0.86g sodium chloride

Hunan Kelun Pharmaceutical Co., Ltd.

• Founded in:

  2001-05-15

• Address:

  Rongxin Road, Chengguan Town, Yueyang County (No. 3, County Ecological Industrial Park)

• Tax NO.:

  914306217459296826

• Registered Funds:

  82 million yuan

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