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Cetirizine Hydrochloride Capsules

Function and Efficacy

[Pharmacology and Toxicology] Pharmacology: This product is a selective histamine H1 receptor antagonist, with no obvious anticholinergic or anti-5-hydroxytryptamine effects, and a mild central inhibitory effect. Toxicology: [Pharmacokinetics] According to reports, cetirizine hydrochloride is rapidly absorbed from the gastrointestinal tract after oral administration. For healthy adults, taking 10 mg orally, the peak time (Tmax) of blood drug concentration is 30-60 minutes, the peak blood drug concentration (Cmax) is 300ng/ml, the plasma half-life is about 10 hours, and about 70% of the original drug is excreted from the urine, and a small amount is excreted from the feces. Cetirizine has a high protein binding rate.

Ingredients

The main ingredient of this product is cetirizine hydrochloride, and its chemical name is (±)-2-[2-[4-[(4-chlorophenyl)benzyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride.

Name Description Content CAS NO. Manufacturer
Cetirizine dihydrochlorideIngredients

This product is a selective histamine H1 receptor antagonist with no obvious anticholinergic or anti-5-hydroxytryptamine effect and a mild central inhibitory effect.

More
83881-52-1 57

Appearance

This product is a capsule, and the contents are white or off-white powder.

Indication

Used for seasonal or perennial allergic rhinitis and urticaria.

Usage and Dosage

Oral administration. Adults or children over 12 years old, 10 mg (1 tablet) each time, once a day. Or follow the doctor's advice. If obvious adverse reactions occur, the drug should be discontinued.

Adverse Reactions

Adverse reactions are mild and transient, including drowsiness, sleepiness, headache, dizziness, agitation, dry mouth, and gastrointestinal discomfort. Occasionally, aspartate aminotransferase is slightly elevated.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not for use by pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

No interactions with other drugs have been reported, but caution should be exercised when taking sedatives at the same time.

Storage

Keep in a light-proof and airtight container.

Packaging Specification

10mg

Validity Period

24 months

Manufacturer

Beijing Continent Pharmaceuticals Co., Ltd.

  • Founded in:

    2006-06-19
  • Address:

    No. 60, Shunkang Road, Linhe Industrial Development Zone, Shunyi District, Beijing
  • Tax NO.:

    91110113740421011B
  • Registered Funds:

    70.50281 million yuan
  • Website:

  • Email:

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