Danazol Suppositories

This product is a synthetic steroid hormone that reduces estrogen levels and causes atrophy of normal and ectopic endometrium, and also has weak androgenic activity. The mechanism of action of this product is to inhibit the pituitary-ovarian axis, inhibit the secretion and release of chorionic gonadotropin and luteinizing hormone, and produce a direct inhibitory effect on the target organs of the gonads by binding to reproductive hormone receptors.

Danazol Suppositories

This product is a light yellow conical suppository.

Used for endometriosis with obvious dysmenorrhea symptoms but mild signs.

For vaginal administration, 1 tablet each time, 1 to 2 times a day. Stop use for 3 to 4 days during menstruation. One course of treatment is 3 to 6 months, or follow the doctor's advice.

Occasionally, there may be vulvar itching or mild weight gain. Oral preparations have had the following adverse reactions: androgen-like effects, including weight gain, acne, seborrhea, mild hirsutism, edema, and hair loss. Voice changes, such as hoarseness, instability, and low pitch, which may persist after discontinuation of the drug, and rare clitoral hyperplasia. Other possible endocrine effects include changes in the menstrual cycle and amenorrhea. Cyclic bleeding and ovulation can resume 60 to 90 days after discontinuation of the drug, but persistent amenorrhea is occasionally reported. Hot flushes, sweating, vaginal dryness, irritation, and breast reduction reflect a decrease in estrogen. Mental and emotional disturbances have been reported. There have been reports of elevated serum transaminases or jaundiced liver damage at doses of 400 mg or more per day, so laboratory tests and clinical observations are required during oral treatment to monitor the patient's liver function.

The following patients are contraindicated to use this product: 1. Patients with undiagnosed abnormal vaginal bleeding; 2. Patients with obvious damage to liver, kidney and heart function; 3. Pregnant and lactating women; 4. Patients with porphyria; 5. Patients with thrombosis; 6. Patients with androgen-dependent tumors.

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.

Not yet clear.

Keep in a light-proof and sealed container. Validity period: tentatively two years

50 mg

24 months.

Jiangsu Lianhuan Pharmaceutical Co., Ltd.

• Founded in:

  2000-02-22

• Address:

  No. 9, Jiankang 1st Road, Yangzhou Bio-Health Industrial Park, Yangzhou City, Jiangsu Province

• Tax NO.:

  91321000714094280W

• Registered Funds:

  285.45627 million yuan

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